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Leone (3-4) gave up two runs on two hits while striking out one over one-third of an inning to take the loss against San Diego on Wednesday.

The right-hander had excelled in his previous stints as an opener, but he couldn't get it done against the Padres on Wednesday. Leone allowed a pair of hits to open the contest, and though he followed by striking out Manny Machado, both runners eventually came around to score after his departure. San Francisco is still dealing with a shorthanded rotation, so Leone could get another turn as an opener depending on when Alex Wood (COVID-19) and Johnny Cueto (elbow) are able to return to the rotation.

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