Watch Now: Fantasy Analysis: Christian McCaffrey (Ankle) Set to Miss Multiple Weeks (4:42)

A continuous onslaught of fantasy football injuries will keep players very busy ahead of Week 3. Dion Lewis rushed for a touchdown and totaled 56 yards from scrimmage on Sunday after Saquon Barkley went down with a season-ending knee injury. Should Lewis be among your prime Week 3 fantasy football waiver wire picks? Tre'Quan Smith caught five passes for 86 yards on Monday Night Football to lead all Saints wide receivers. Should Smith be one of your Week 3 NFL fantasy football picks?

Which players on the fantasy football waiver wire are worth grabbing before the Week 3 NFL schedule unfolds? Before you determine which players you should target, be sure to see what SportsLine's Scott Engel has to say.

Engel is an inaugural member of the Fantasy Sports Writers Association's Hall of Fame. He is a four-time FSWA Award Winner and nine-time finalist, and has pulled off a three-peat in his prestigious New York City Fantasy Football League that includes other experts and high-stakes players. If there's anyone who knows what it takes to win a league, it's him. Engel went 13-3 in his seasonal Fantasy Football leagues in Week 1. 

Now, he's revealed the best widely available Fantasy football free agents entering Week 3. You can see his top Fantasy NFL waiver wire picks and full analysis over at SportsLine

Top Fantasy football waiver wire picks for Week 3

One player Engel is advising Fantasy players to target on the Week 3 waiver wire: Colts wide receiver Michael Pittman Jr. Last week, Parris Campbell was a prime waiver add as he drew frequent looks from new quarterback Philip Rivers, who prefers to go with a high-percentage passing approach at this point of his career. But Campbell left Sunday's game with a knee injury and Pittman was called on to step in for Campbell as a key target for Rivers. 

The rookie wideout tied for the team lead in targets on the day with six, and may have to play a significant role in the offense while Campbell sits out with yet another injury. Pittman is a big receiver who can be essential for Rivers when he attempts to move the chains on important passing downs. With his size and strength, he also figures to get looks in goal-line situations. More opportunity could lead to increased production from Pittman. He also has a tasty Week 3 matchup against the Jets

Another waiver wire target he's all over entering Week 3: Panthers running back Mike Davis. Christian McCaffrey is expected to miss four to six weeks with an ankle injury, so Davis will become the primary back for Carolina while their franchise player is out. Davis showed he could immediately step in as an effective pass-catching running back, as he caught all eight of his targets for 74 yards against Tampa Bay.

New Panthers coach Matt Rhule has openly praised Davis for his versatility. In the past when called on to assume a larger role, Davis has also displayed plenty of vision and the ability to evade defenders to gain extra yardage. Davis has already shown he can take advantage of an opportunity and he doesn't have much mileage on his tires at age 27. In fact, he has never had more than 112 carries in a season.

How to set your Week 3 waiver wire claims

Engel is also all-in on an overlooked wide receiver who has massive upside. This player is still widely available and could be a huge boost to your Fantasy football roster moving forward. You can only see who it is at SportsLine

So which players should you target on the Fantasy football waiver wire before Week 3? And which overlooked wide receiver could help lead your team to Fantasy glory? Visit SportsLine now to see the best league-winning Fantasy football free agents entering Week 3, all from a Fantasy Hall of Famer, and find out.