Cunningham (undisclosed) was placed on the reserve/COVID-19 list Friday.

The timing of the move all but rules Cunningham out for Sunday's game against Buffalo, and there's no guarantee he'll come off the list in time to dress for Houston's Week 5 game against the Patriots. Cunningham's absence will make it even harder for the heavy underdog Texans to upset the Bills, as he's coming off a 14-tackle Week 3 performance.

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