The San Diego Padres will attempt to break out of a mini skid Friday when they host the Milwaukee Brewers in the second of a four-game home weekend series. First pitch is set for 9:40 p.m. ET from Petco Park in San Diego. Michael Wacha (2-0, 3.00 ERA) will look for this third consecutive victory to start the season for the Padres (7-7), who have lost three of their past four. Wacha has never lost against the Brewers, going 6-0 with an ERA of 3.38 in 14 career starts, all of which came while the pitcher was with the St. Louis Cardinals. The Brewers (9-4), who won the series opener 4-3 on Thursday, counter with left-hander Eric Lauer (1-1, 7.71). He allowed six earned runs over four innings in a 6-0 loss to the Cardinals in his last outing.
For Friday, the Padres are -170 favorites (risk %170 to win $100), while the Brewers return a price of +145 in the latest Caesars Sportsbook MLB odds. The over/under for total runs scored is 8.5. That's one of 15 games on the Friday MLB schedule. Before making any MLB picks or parlays, be sure to check out the MLB predictions and betting advice from SportsLine's proven computer simulation model.
The SportsLine Projection Model simulates every MLB game 10,000 times. It went 331-285 on top-rated MLB money-line picks (+357) over the past two seasons, and it finished the 2022 MLB season on a 20-14 roll. Anyone who has followed it has seen profitable returns.
For Tuesday, the model has locked in four confident MLB best bets for games that begin after 8 p.m. ET. If you successfully parlay the picks, you'd be looking at a payout of well over 10-1. You can see the model's top picks at SportsLine.
Top MLB picks today
After simulating every game on Friday 10,000 times, the model is backing the Los Angeles Dodgers (-165) over the Chicago Cubs (+140) as one of its top selections. The model sees Los Angeles winning this matchup in a whopping 74% of simulations, and by nearly two full runs per simulated outcome.
Following a three-game skid, the Dodgers (7-6) moved above the .500 clip by taking two of three from the NL West rival San Francisco Giants on the road, including a 10-5 victory Wednesday after they rallied from a 3-0 deficit.
Los Angeles will send out right-hander Noah Syndergaard (0-1, 6.30), who will attempt to bounce back from a rough outing. He gave up six runs over four innings in a 12-8 loss to the Arizona Diamondbacks last Saturday. The Dodgers have taken 10 of the past 11 meetings against the Cubs, who will go with left-hander Justin Steele (1-0, 0.75). You can see who else to back at SportsLine.
How to make MLB parlays for April 14
The model also locked in three other best bets for Friday, including one on a big underdog. You can see the model's MLB best bets and parlay only at SportsLine.
What MLB picks should you target for a payout of well over 10-1? And which team that pays plus-money does the model like on Friday? Visit SportsLine now to see the MLB best bets from an advanced model that ended last season on a 20-14 roll on top-rated money-line picks, and find out.
