The San Diego Padres (47-35) host the Seattle Mariners (40-42) to conclude their brief two-game series on Tuesday afternoon. San Diego has been in a slump lately, dropping four of its last five games. Meanwhile, Seattle is currently on a three-game winning streak. Both teams sit in second place in their respective divisions. It's a strong pitching matchup with the Mariners starting Logan Gilbert (9-3, 2.66 ERA), while the Padres are sending Mike Clevinger (2-0, 2.79 ERA) to the hill.

First pitch is set for 4:10 p.m. ET. Caesars Sportsbook lists San Diego as the -135 favorite (risk $135 to win $100) on the money line, while Seattle is the +115 underdog. The over-under for total runs is set at 7.5. Before making any Mariners vs. Padres picks, you need to see the MLB predictions and betting advice from SportsLine's advanced computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times. and it is 271-232 on top-rated MLB money-line picks since the start of the 2021 season, returning well over $500 for $100 players. This is the same model that pegged the 2021 Atlanta Braves at 10-1 as one of three best bets to win it all last season. Anybody who has followed it has seen profitable returns.

Now, the model has set its sights on Padres vs. Mariners, and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model's picks. Here are several MLB odds and betting lines for Mariners vs. Padres

  • Padres vs. Mariners money line: Padres -135, Mariners +115
  • Padres vs. Mariners over-under: 7.5 runs
  • Padres vs. Mariners run line: Padres -1.5 (+158)
  • SD: The Padres are 6-0 (+470) when Clevinger starts 
  • SEA: The Mariners are 11-5 when Gilbert starts 
  • Padres vs. Mariners picks: See picks at SportsLine
Featured Game | San Diego Padres vs. Seattle Mariners

Why you should back the Padres

Left fielder Jurickson Profar is a versatile playmaker. Profar has a combination of power, speed and plate awareness. The 29-year-old is able to drive the ball into gaps for extra-base hits. He is batting .243 with eight home runs and 38 RBIs. On July 1, he went 2-for-4 with two doubles.

First baseman Eric Hosmer is a solid defender on the corner. Hosmer has displayed home-run power with a left-handed stroke. The 32-year-old has a batting average of .273 with six home runs and 33 RBIs. On July 3, he was 2-for-4 with an RBI and one run scored. 

Why you should back the Mariners

Center fielder Julio Rodriguez is an athletic force for the Mariners. Rodriguez has terrific speed to cover plenty of ground in the outfield while having a superb swing. The 21-year-old has home-run power and run-producing qualities. He is hitting .275 with 15 home runs and 43 RBIs. Rodriguez rolls into this game on an eight-game hitting streak.

Third baseman Eugenio Suarez is a good defender who owns an excellent throwing arm. Suarez has a smooth swing with power to any gap of the field. The one-time All-Star currently has 13 dingers and 38 RBIs. On June 3, he went 2-for-3 with two singles. 

How to make Mariners vs. Padres picks

SportsLine's model is going over on the total, projecting 8.2 combined runs. It also says one side of the money line has all the value. You can only get the model's MLB picks at SportsLine.

So who wins Padres vs. Mariners? And which side has all the value? Visit SportsLine now to see which side you need to jump on, all from the model that has crushed its MLB picks, and find out.