The Indianapolis Colts (6-5) will host the Tampa Bay Buccaneers (7-3) at 1 p.m. ET Sunday at Lucas Oil Stadium in Indianapolis. The Colts have won five of their last six games and are 3-3 at home. Tampa has lost its last two road games and two of its last three overall. These teams last met in 2019 in which the Bucs prevailed 38-35.
Tampa Bay is favored by 2.5 points in the latest Colts vs. Buccaneers odds from Caesars Sportsbook, and the over-under is set at 53. Before entering any Buccaneers vs. Colts picks, you'll want to see the NFL predictions from the model at SportsLine.
The model, which simulates every NFL game 10,000 times, is up almost $7,300 for $100 players on top-rated NFL picks since its inception six-plus years ago. The model enters Week 12 of the 2021 season on an incredible 130-91 run on top-rated NFL picks that dates back to the 2017 season.
The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.
Now, the model has set its sights on Colts vs. Buc. You can head to SportsLine to see its picks. Here are several NFL betting lines for Bucs vs. Colts:
- Colts vs. Buccaneers spread: Colts +2.5
- Colts vs. Buccaneers over-under: 53 points
What you need to know about the Colts
The Colts easily handled the Bills in Week 11 by a score of 41-15. The 264 rushing yards by Indy was its third-most in a game since 1985. Jonathan Taylor led the way in the backfield with 185 rushing yards, 19 receiving yards and five total touchdowns.
Taylor leads the NFL in rushing yards (1,122), yards from scrimmage (1,444) and touchdowns (15). The Colts are 6-0 when he rushes for at least 100 yards and 0-5 when he fails to reach the century mark. Quarterback Carson Wentz has thrown just three interceptions this year after leading the league with 15 picks last season.
What you need to know about the Buccaneers
The Buccaneers strolled past the New York Giants last week, 30-10. Tom Brady passed for 307 yards and two TDs. He leads the NFL with 29 TD passes and is tied for the most 300-yard games with five. Mike Evans caught his 10th TD pass and is tied for the league lead.
Chris Godwin has five-plus catches in his last six games. Vita Vea (knee) and Devin White (quadriceps) are questionable for Sunday's game. Ali Marpet (oblique) is doubtful and Antonio Brown (ankle) remains out.
How to make Colts vs. Buccaneers picks
The model is leaning over on the total, and it's also generated a point-spread pick that is hitting in 60 percent of simulations. You can only see the pick at SportsLine.
So who wins Colts vs. Buccaneers? And which side of the spread hits 60 percent of the time? Visit SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NFL picks.
