Williams suffered an apparent left leg injury late in the third quarter of Saturday's 37-23 loss to the Panthers and didn't return, Kyle Meinke of MLive.com reports.
Williams appeared to suffer the injury on a third-down reception with 3:53 remaining in the quarter. Given that Detroit trailed by 18 points when Williams exited, it's possible he was withheld from the remainder of the contest due to D'Andre Swift being the team's preferred back in the hurry-up offense. Williams finished Saturday's contest with seven carries for 11 yards and two receptions for three yards.