The Buffalo Bills will host a playoff game for the second consecutive week when they welcome the Baltimore Ravens on Saturday. Buffalo narrowly defeated the Indianapolis Colts last week to remain alive in the 2021 NFL Playoffs. Also in the Wild Card round, the Ravens toppled the Tennessee Titans in Nashville behind a strong defensive effort. The winner of this matchup will face the winner of Kansas City Chiefs vs. Cleveland Browns with a trip to the Super Bowl on the line.

Kickoff is at 8:15 p.m. ET. William Hill Sportsbook lists Buffalo as a 2.5-point home favorite, while the over-under, or total number of points Vegas thinks will be scored, is 49.5 in the latest Bills vs. Ravens odds. Before making any Ravens vs. Bills picks, see the latest NFL predictions and betting advice from SportsLine's proven model.

The model, which simulates every NFL game 10,000 times, is up almost $7,900 for $100 players on top-rated NFL picks since its inception five-plus years ago. It is a sizzling 24-14 on top-rated NFL picks this season, returning well over $800. The model also enters the Divisional Round of the 2021 NFL Playoffs on an incredible 120-78 run on top-rated NFL picks that dates back to the 2017 season.

The model ranked in the Top 10 on NFLPickWatch three of the past four years on straight-up NFL picks and beat more than 95 percent of CBS Sports office pool players three times during that span. Anyone who has followed it is way up. 

Now, the model has set its sights on Bills vs. Ravens. You can head to SportsLine to see its picks. Now, here are the latest NFL odds and trends for Ravens vs. Bills:

  • Ravens vs. Bills spread: Bills -2.5
  • Ravens vs. Bills over-under: 49.5 points
  • Ravens vs. Bills money line: Bills -145, Ravens +125
  • BAL: Ravens are 11-6 against the spread this season
  • BUF: Over has hit in 11 Bills games

Why the Ravens can cover

Baltimore is an exceptional defensive team, which was on full display in the team's win over the Titans. Tennessee was a top-10 offensive team in 2020, but the Ravens held the Titans to just 209 total yards and 51 rushing yards. That wasn't a fluke, either, as Baltimore also finished in the top eight in total defense, run defense and pass defense, all while giving up only 18.9 points per game.

The Ravens are on the short list of teams best equipped to slow down Bills quarterback Josh Allen and wide receiver Stefon Diggs. Baltimore went 11-5 against the spread this season and has covered seven straight games.

Why the Bills can cover

Buffalo is one of the best offensive teams in the NFL, but the majority of the success can be attributed to the duo of quarterback Josh Allen and wide receiver Stefon Diggs. Diggs led the NFL in both receptions and receiving yards this season, experiencing a full-fledged breakout in a thoroughly dominant campaign.

As for Allen, the talented signal-caller finished in the top five of the NFL in total offense (4,806 yards), completions (396), passing yards (4,544), passing touchdowns (37), passer rating (107.2), yards per attempt (7.9), QBR (81.7) and completion percentage (69.2 percent). On top of his gifted arm talent, Allen is a threat on the ground, making life difficult for the opposition, and the Bills were a top-three total offense in the NFL in yardage and scoring because of his impact.

How to make Bills vs. Ravens picks

SportsLine's model is leaning under on the total, with the simulations showing the teams combining for 49 points. The model also says one side of the spread hits well over 50 percent of the time. You can only see which side to back here.

So who wins Ravens vs. Bills in the 2021 NFL Playoffs? And which side of the spread hits well over 50 percent of the time? Visit SportsLine now to find out which side of the Ravens vs. Bills spread you need to jump on Saturday, all from the model on a 120-78 roll, and find out.