Seahawks quarterback Russell Wilson has missed more than a month of action due to an injury, but he is back on the field. Wide receiver Tyler Lockett had several poor weeks with Wilson sidelined, so his owners are happy to have the latter in the lineup. Lockett caught four passes for 115 yards in a loss to Arizona last week, making him one of the most productive players in Week 11. Should Lockett be among your Week 12 Fantasy football picks?

The Seahawks will face a Washington defense that is allowing 368.5 yards per game, which puts them in the bottom third of the league. Where should Wilson and Lockett be in the Week 12 Fantasy football rankings? Before you lock in your Week 12 Fantasy football picks, be sure to check out the Week 12 Fantasy football predictions from the proven computer model at SportsLine.

When it comes to ranking players, SportsLine's model beat human experts in Fantasy football for the past several seasons especially when there were big differences in ranking. Over the course of a season, that could literally be the difference between winning your league or going home emptyhanded.

Last week, the model was extremely high on Bengals running back Joe Mixon, saying he'd finish as a top-five running back for the week. The result: Mixon rushed for 123 yards and two touchdowns in a Bengals win. Anybody who had him in their lineup was well on their way to a huge week.

Now, the model, which simulates every NFL game 10,000 times, has revealed its Fantasy football rankings for Week 12 of the 2021 NFL season. Head to SportsLine now to see them.

Top Week 12 Fantasy football picks 

One player the model is high on this week: Colts quarterback Carson Wentz. The 28-year-old has posted smaller numbers in the Colts' double-digit victories this season, averaging just 25.6 pass attempts in those games. That should not be an issue this week since Indianapolis will face the reigning Super Bowl champions. Opponents are throwing against Tampa Bay 67 percent of the time, the highest rate of any team in the NFL.

Wentz completed 27-of-51 passes for 231 yards and three touchdowns in a close game against Tennessee several weeks ago. The Colts should air the ball out on Sunday given the Buccaneers' stout run defense. Fire him up as part of your Fantasy football lineups.

And a massive shocker: Titans quarterback Ryan Tannehill, who was started in 74 percent of CBS Sports Fantasy football leagues last week, stumbles big-time and doesn't even crack the top 25 at his position. Tannehill has reinvented himself since taking over as Tennessee's starter in the middle of the 2019 season, but much of his success has been predicated on the Titans' ability to run the ball, which has been tough since Derrick Henry (foot) got hurt.

Tannehill has averaged just 6.4 yards per pass attempt in the three weeks since Henry was hurt and last week when the Titans were forced to throw often while playing from behind, it was a struggle. Tannehill threw four interceptions and averaged just 6.2 yards per pass attempt despite completing 67.3 percent of his throws. He'll take on the Patriots on Sunday, who rank No. 3 in the NFL in total defense, which is why the model ranks Tannehill outside its top 25 options at quarterback in Week 12.

How to set Week 12 Fantasy football rankings

The model is also calling for a surprising quarterback you aren't even thinking about to finish in the top 10 of its Fantasy football rankings. This pick could be the difference between winning big and going home with nothing. You can only see who it is here.

So who should you start and sit this week? And which surprising quarterback could lead you to victory? Visit SportsLine now to get Week 12 Fantasy football rankings for every position, plus see which QB is going to come out of nowhere to crack the top five, all from the model that has out-performed experts big-time.