The Week 8 college football schedule features zero ranked vs. ranked matchups, but this sport still finds a way to make every weekend special. That means the potential for an earth-shattering upset is high. No. 2 Cincinnati is -28 against Navy, No. 3 Oklahoma is -38.5 against Kansas, No. 4 Alabama is -25 against Tennessee and No. 5 Ohio State is -21 against Indiana, per the Week 8 college football odds at Caesars Sportsbook.

Whether you're looking to take on one of these giant spreads or looking to bet on something closer like No. 10 Oregon (-2) vs. UCLA or No. 8 Oklahoma State against Iowa State (-7), some expert advice can go a long way. Where are the best values in the Week 8 college football lines? Before locking in any college football bets on Saturday, be sure to see the top Week 8 college football expert picks, predictions and best bets from Barrett Sallee.

Sallee is a true insider -- a CBS Sports analyst, SiriusXM host, Heisman voter and consistently one of the top CBS Sports experts picking games against the spread -- and his best bets have helped bring in huge returns. He debuted with SportsLine in 2017 and has delivered in a big way on his college football picks

Over the past two-plus years, he is 90-68 in his popular best bets column at SportsLine. Anybody who has been following him is way up.

Now, he has turned his attention to the Week 8 college football odds from Caesars and is sharing his top three best bets over at SportsLine. If you parlay them together, you could be looking at a return of around 6-1. Get his top college football picks now

Top Week 8 college football expert predictions

One of Sallee's top college football picks for Week 8: He's backing No. 8 Oklahoma State (+7) at Iowa State in a 3:30 p.m. ET matchup on Saturday.

Oklahoma State running back Jaylen Warren has burst onto the scene in the Big 12, rushing for 705 yards and six touchdowns. He ran wild in a 32-24 win over Texas last week, finishing with 193 rushing yards on 33 carries. The Cowboys have now knocked off three ranked teams this season and are undefeated coming into this matchup.

Iowa State has lost to the top two teams it has faced (Iowa, Baylor) this year. The Cyclones rank third nationally in total defense, but they have not played the best offensive teams in the conference. Oklahoma State has covered the spread in four of its last five games this year and has won eight of its last nine contests against Iowa State. 

"This game has all of the makings of an old-school slugfest," Sallee told SportsLine. "A full touchdown spread seems a bit aggressive here."

Featured Game | Iowa State Cyclones vs. Oklahoma State Cowboys

How to make Week 8 college football picks 

Sallee has also found two other college football picks he's high on, including a must-see play on a slight favorite that he believes wins by double digits. You can only see his picks at SportsLine.

What are the best bets for Week 8 of college football? And which college football picks need to be part of your parlays? Visit SportsLine now to see Barrett Sallee's college football best bets, all from one of the top analysts in the nation who has crushed his picks for SportsLine.