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The Week 10 NFL schedule opens with a Thursday Night Football NFC South rivalry with P.J. Walker and the Carolina Panthers hosting Marcus Mariota and the Atlanta Falcons at Bank of America Stadium. The teams met in Week 8 with Atlanta notching a thrilling 37-34 overtime win. In a game where the weather forecast will definitely play a factor, there will be little room for error when building your NFL DFS lineups and NFL DFS stacks. Given the weather, should Atlanta running back Cordarrelle Patterson be considered a must-start option in your TNF Showdown NFL DFS strategy? Or would it make sense to look at quarterbacks, tight ends, wide receivers, or other running backs,in the TNF NFL DFS player pool? Kyle Pitts, Drake London, Chuba Hubbard, D'Onta Foreman, D.J. Moore, and Terrace Marshall Jr. all project to be impact classic and showdown NFL DFS picks for Thursday Night Football.

Before making any Thursday NFL DFS picks for Falcons vs. Panthers on sites like DraftKings and FanDuel of your own, be sure to check out the NFL DFS lineup advice, strategy and player stacks from SportsLine NFL daily Fantasy expert Jimmie Kaylor

Kaylor is an NFL and DFS expert for SportsLine, who opened the 2022 NFL season by winning DraftKings' NFL Showdown Thursday Kickoff Millionaire contest. He edged out over 355,000 other entrants in the contest and also has multiple five-figure tournament wins on his DFS resume. Kaylor has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America, and his background as a former college and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks.

Kaylor has been spot-on all season, hitting on epic NFL DFS picks in primetime showdown matchups like Jerry Jeudy (4-102-1), Stefon Diggs (12-148-3), Amari Cooper (7-101-1), Nick Chubb (23-113-1), CeeDee Lamb (8-87-1), Deebo Samuel (6-115-1) Cooper Kupp (14-122), Travis Kelce (7-25-4), Davante Adams (3-124-2), Justin Fields (179-1-1, 82-1), Diggs again in Week 8 (6-106-1), Chubb (23-101-2) and Cooper (5-131-1) again on MNF in Week 8, and Kelce again on Week 9 SNF (10-106). Anyone who has followed his picks is way up.

Now, Kaylor has turned his attention to Panthers vs. Falcons on Thursday Night Football Week 10 and locked in his top daily Fantasy football picks. You can only see his picks and analysis at SportsLine.

Top NFL DFS picks for Falcons vs. Panthers on TNF

One of Kaylor's top showdown DFS picks for the Atlanta vs. Carolina game on TNF is Falcons running back Cordarrelle Patterson. In a game where rain and wind could factor in, both teams will likely lean on their rushing attacks. Patterson is one of the most dynamic players in the NFL and head coach Arthur Smith's offensive system is nearly perfect for his unique skillset. The Panthers have had major issues stopping the run as of late, and Kaylor thinks Patterson could thrive on Thursday Night Football.

"The Panthers have one of the premier young edge rushers in the NFL in Brian Burns, but their front seven has been a liability against the run in their last two games. The Falcons ran for 167 yards against the Carolina defense in Week 8, and that was with Cordarrelle Patterson sidelined due to injury. The Panthers followed that performance up by allowing the Bengals to rush for 241 yards (with Joe Mixon going for 153 yards and 4 TDs) a week later. Patterson may lose some carries to Tyler Allgeier, but I fully expect the Falcons' offense to run through the former first round pick on Thursday night. Expect to see Patterson end up with close to 20 touches and over 100 all-purpose yards," Kaylor told SportsLine. You can see the rest of Kaylor's NFL DFS picks here.

How to make NFL DFS lineups for Panthers vs. Falcons on TNF

Kaylor is also targeting another undervalued option that could explode for huge numbers for Thursday Night Football. This pick could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who it is, and the rest of Kaylor's TNF DFS picks, at SportsLine

So who is Jimmie Kaylor including in his optimal NFL DFS lineups for Thursday Night Football? And which under-the-radar DFS picks offer huge value? Visit SportsLine now to see optimal NFL DFS picks, rankings, advice, and stacks, all from a DFS expert who already won a single-game millionaire maker tournament in 2022, and find out.