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The Week 10 NFL schedule wraps up with a battle between longtime NFC East rivals with Jalen Hurts and the Philadelphia Eagles hosting Taylor Heinicke and the Washington Commanders on Monday Night Football. The latest Eagles vs. Commanders odds suggest that this MNF game will be one-sided in favor of Philadelphia, but that doesn't mean you should ignore the players on the Washington side in the MNF NFL DFS player pool when building your MNF NFL DFS strategy. With his team projected to be playing from behind for most of the night, should Heinicke be considered a must-start player in your NFL DFS lineups and NFL DFS stacks? Or should you build around a running back, wide receiver, tight end, or D/ST? A.J. Brown, Miles Sanders, Dallas Goedert, DeVonta Smith, Brian Robinson Jr., Antonio GibsonTerry McLaurin, and Curtis Samuel all project to be impact classic and showdown NFL DFS picks for Monday Night Football. 

Before making any NFL DFS picks for Commanders vs. Eagles on sites like DraftKings and FanDuel, be sure to check out the NFL DFS lineup advice, strategy and player stacks from SportsLine NFL daily Fantasy expert Jimmie Kaylor

Kaylor is a NFL and DFS expert for SportsLine, who opened the 2022 NFL season by winning DraftKings' NFL Showdown Thursday Kickoff Millionaire contest. He edged out over 355,000 other entrants in the contest and also has multiple five-figure tournament wins on his DFS resume. Kaylor, who has been cashing big all season, has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America, and his background as a former college and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks.

Kaylor has been spot-on all season, hitting on epic NFL DFS picks like Jerry Jeudy (4-102-1), Stefon Diggs (12-148-3), Amari Cooper (7-101-1), Nick Chubb (23-113-1), CeeDee Lamb (8-87-1), Deebo Samuel (6-115-1) Cooper Kupp (14-122), Travis Kelce (7-25-4), Davante Adams (3-124-2), Justin Fields (179-1-1, 82-1), Diggs again in Week 8 (6-106-1), Chubb (23-101-2) and Cooper (5-131-1) again on MNF in Week 8, and Kelce again in Week 9 SNF (10-106). Anyone who has followed his picks is way up.

Now, Kaylor has turned his attention to Eagles vs. Commanders on Monday Night Football Week 10 and just locked in his top daily Fantasy football picks. You can only see his picks and analysis at SportsLine.

Top NFL DFS picks for Commanders vs. Eagles on MNF

One of Kaylor's top MNF DFS picks for the Philadelphia-Washington Monday Night Football matchup is Eagles wide receiver DeVonta Smith. The former first round pick out of Alabama is the No. 2 option in the Eagles passing attack, but that isn't scaring Kaylor away from building his DFS rosters around Smith on Monday night.

"It may seem risky to target a guy who isn't even the No. 1 option on his own team, but I'll be doing just that with DeVonta Smith on Monday night. After back-to-back games with sub-standard DFS production, I believe Smith is primed to blow up for a huge night against the Commanders. In Philadelphia's first meeting with Washington in Week 3, the 2020 Heisman Trophy winner caught eight passes for 169 yards and a touchdown. Those numbers may be tough to duplicate, but I see something similar happening on Monday Night Football," Kaylor told SportsLine. You can see the rest of Kaylor's NFL DFS picks here.

How to build NFL DFS lineups for Eagles vs. Commanders on MNF

Kaylor is also targeting another undervalued value who could explode for huge numbers for Monday Night Football. This pick could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who it is, and the rest of Kaylor's MNF DFS picks, at SportsLine

So who is Jimmie Kaylor including in his optimal NFL DFS lineups for Monday Night Football? And which under-the-radar NFL DFS picks offer huge value? Visit SportsLine now to see optimal NFL DFS picks, rankings, advice, and stacks, all from a DFS expert who already won a single-game millionaire maker tournament in 2022, and find out.