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The Tampa Bay Buccaneers can join Arizona and Green Bay as the teams with the best record in the NFL when they take on the New Orleans Saints on Sunday. With Green Bay's win over Arizona on Thursday, the Buccaneers (6-1) enter Sunday a half-game behind the Cardinals and Packers for the best record in the league. The Saints (4-2) sit in second place in the NFC South behind Tom Brady and company. Tampa Bay is a 4.5-point favorite in the latest NFL odds from Caesars Sportsbook, but which team should you back with your NFL bets and NFL parlays?

Other key matchups include Titans vs. Colts in a battle of the top two teams in the AFC South and Sunday Night Football between the Cowboys and Vikings. Before locking in any Week 8 NFL picks or predictions, you need to check out the NFL best bets from the proven computer model at SportsLine

The model, which simulates every NFL game 10,000 times, is up almost $7,700 for $100 players on top-rated NFL picks since its inception six-plus years ago. It went a sizzling 24-14 on top-rated NFL picks last season, returning more than $800. The model also enters Week 8 of the 2021 season on an incredible 126-85 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has locked in five confident NFL best bets for Week 8. If you successfully parlay its picks, you'd be looking at a massive payout of 25-1. You can only see the model's Week 8 NFL picks at SportsLine

Top Week 8 NFL picks

After simulating every NFL game 10,000 times, the model is high on the Bills to cover as 13.5-point favorites at home against the Dolphins. Three weeks ago, Buffalo dominated the two-time defending AFC champion Kansas City Chiefs to stake a claim as one of the top teams in the league. After falling at Tennessee one week later, the Bills took a week off for their bye. Miami has lost back-to-back games on last-second field goals.

Buffalo has dominated the recent series against Miami. The Bills have won six straight against the Dolphins, a streak that dates back to the 2018 season. Buffalo has scored at least 31 points in each of the six games, and its average margin of victory has been 20 points per game. The streak includes a 35-0 blowout in Miami in Week 2.

How to make Week 8 NFL parlays

The model also jumped on four other matchups where it says the line is way off, including a divisional battle and a game between two teams fighting for their playoff lives. You can only see the model's NFL Week 8 best bets and parlay at SportsLine

What are the model's top Week 8 NFL picks? And which other matchups should you target for an epic 25-1 payout? Visit SportsLine now to see the Week 8 NFL best bets from a model on a 126-85 run on its top-rated picks, and find out.