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Ben Queen / USA TODAY Sports

The 2020 college football season has been an unusual one with the coronavirus pandemic undoing years of scheduling in a matter of months. The start of conference play, however, has already brought plenty of excitement. Texas made a thrilling comeback to beat Texas Tech in overtime last week. Now the No. 9 team in the nation will host TCU on Saturday at noon ET as a 13-point favorite in the Week 5 college football odds from William Hill. 

Meanwhile, No. 4 Georgia is a 6.5-point favorite over No. 7 Auburn in the latest Week 5 college football spreads. USC transfer JT Daniels has been medically cleared, but will the Bulldogs go with the former five-star over D'Wan Mathis and Stetson Bennett at quarterback? Before making any Week 5 college football picks on those games or others, be sure to see the latest college football predictions from SportsLine's proven model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past four-plus years, the proprietary computer model has generated a stunning profit of over $4,000 for $100 players on its top-rated college football picks against the spread. It is a sizzling 16-2 on top-rated picks through four weeks of the 2020 college football season, returning over $1,100 in profit already. Anybody who has followed it is way up. 

Now, it has turned its attention to the latest college football odds for Week 5 from William Hill and locked in picks for every FBS matchup. Head to SportsLine to see every pick.

Top Week 5 college football predictions 

One of the top Week 5 college football picks the model is recommending: Texas (-13 at William Hill) gets the win and the cover at home in a noon ET kickoff against TCU on Saturday. The Longhorns survived in a 63-56 shootout against Texas Tech in Week 4. TCU, meanwhile, fell at home against Iowa State.

SportsLine's model is calling for another big day for Texas quarterback Sam Ehlinger. He accounts for over 300 total yards and three scores in the simulations. The Texas defense, however, performs better -- giving up fewer than 20 points, according to the model. Texas gets the cover in well over 50 percent of simulations, making it a great choice for Week 5 college football bets.

Another one of the top Week 5 college football predictions from the model: Baylor goes to West Virginia and covers as a three-point favorite in a noon ET kickoff from Milan Puskar Stadium. Baylor is currently just outside the AP Top 25 Poll after earning a dominant 47-14 win over Kansas last week.

Returning starting quarterback Charlie Brewer didn't have to do much in the victory, completing 15-of-23 passes for 142 yards and a touchdown as the Baylor rushing attack combined for 203 yards and three touchdowns. Brewer threw for 3,161 yards and 21 touchdowns with just seven interceptions in 2019, while adding 11 rushing touchdowns.

West Virginia gave up 203 rushing yards in a loss to Oklahoma State last week, so look for Baylor to continue to attack on the ground on Saturday. The model predicts that the Bears cover in well over 60 percent of simulations, with the under (53.5) hitting nearly 70 percent of the time.

How to make Week 5 college football picks 

The model has also made the call on who wins and covers every other FBS game in Week 5, and it is also predicting a major upset in the SEC. You can only get every pick for every game at SportsLine.

So what college football picks can you make with confidence in Week 5? And which SEC team will pull off a shocking upset? Check out the latest Week 5 college football odds below for some of the week's most notable games, and then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned over $4,000 in profit over the past four-plus seasons, and find out.

Week 5 college football odds (via William Hill)

TCU at Texas (-13)
South Carolina at Florida (-18)
Missouri at Tennessee (-10)
Baylor at West Virginia (+3)
NC State at Pittsburgh (-13.5)
North Carolina at Boston College (+11)
Memphis at SMU (+1.5)
Texas Tech at Kansas State (-3.5)
Oklahoma State at Kansas (+21.5)
Texas A&M at Alabama (-17.5)
Virginia Tech at Duke (+10.5)
Ole Miss at Kentucky (-6.5)
Navy at Air Force (+5.5)
Oklahoma at Iowa State (+7)
Tulsa at UCF (-21)
Auburn at Georgia (-6.5)
LSU at Vanderbilt (+20)
Arkansas at Mississippi State (-17)
Virginia at Clemson (-28)