College football odds, picks, lines, top predictions for Week 8, 2023: Proven model likes Washington, Houston

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Several pivotal conference matchups take center stage during the Week 8 college football schedule. One of the headliners is No. 3 Ohio State hosting No. 7 Penn State in a Big Ten battle. The Buckeyes are 4-point favorites in the Week 8 college football odds according to the SportsLine consensus. No. 2 Michigan is traveling to play Michigan State for an in-state rivalry and the Wolverines are favored by 24 points. And in perhaps the most intriguing SEC showdown of the week, No. 11 Alabama (-8.5) hosts No. 17 Tennessee in the 3:30 p.m. ET SEC on CBS matchup.

Which of those Week 8 college football spreads have value, and how should you play other big matchups such as No. 14 Utah vs. No. 18 USC (-7) or No. 16 Duke vs. No. 4 Florida State (-14)? Before locking in any Week 8 college football picks on those games or others, be sure to see the latest college football predictions from SportsLine's proven model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, it has generated a stunning profit of more than $2,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has turned its attention to the latest college football odds for Week 8 and locked in picks for every FBS matchup. Head here to see every pick.

Top college football predictions for Week 8

One of the college football picks the model is recommending for Saturday: Houston (+23.5) easily stays within the spread against No. 8 Texas at 4 p.m. ET. Houston is coming off a thrilling victory over the West Virginia Mountaineers in their last outing, posting a 41-39 victory at home. The Longhorns, meanwhile, suffered their first loss of the season in their last outing, a 34-30 defeat against Oklahoma on Oct. 7.

Texas was torched by Oklahoma quarterback Dillon Gabriel and now the Longhorns will face a Houston offense that's averaging 29.7 points per game. Houston quarterback Donovan Smith has thrown four touchdowns in each of his past two games, completing over 70% of his passes in both of those contests. Smith is also effective as a runner, carrying the ball 67 times with four rushing scores. In addition, Texas is 0-4-1 against the spread in its last five games against an opponent from the American Athletic Conference. The model projects Houston's offense to put up enough points to stay within the spread with the Cougars covering in more than 70% of simulations.

Another prediction: No. 5 Washington (-27.5) cruises to a blowout win against Arizona State in a 10:30 p.m. ET kickoff at Husky Stadium. Washington is coming off an emotional win at home against Oregon, but the Huskies have the veteran leadership needed to stay focused and come out firing on all cylinders on Saturday.

Senior quarterback Michael Penix Jr. is a legitimate Heisman Trophy contender and he's already thrown for 2,301 yards and 20 touchdowns this season. He threw four touchdown passes in the win over the Ducks and 16 of his 20 touchdowns have come at home. The Sun Devils gave up 322 passing yards and three touchdowns to USC's Caleb Williams on Sept. 23, a big reason why the model projects Penix and the Huskies to cover the spread in well over 60% of simulations. See which other teams the model likes here.

How to make college football picks for Week 8

The model has also made the call on who wins and covers in every other FBS matchup in Week 8, and it's calling for several underdogs to win outright. You can only get every pick for every game at SportsLine.

So what college football picks can you make with confidence, and which underdogs win outright? Check out the latest college football odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned more than $2,000 in profit since its inception, and find out.