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The opening week of the 2022 USFL season featured several innovations to help separate it from other football leagues, as well as mostly competitive games to keep the fans engaged. Three of the four games were decided by one score, which has spurred plenty of interest for the Week 2 USFL schedule. One game took place on Friday night as the Generals beat the Panthers 10-6, with two games set for Saturday and then one on Sunday afternoon. The Week 2 finale on Sunday features the Tampa Bay Bandits (1-0) taking on the New Orleans Breakers (1-0).

Tampa was the only team who won by more than six points last week as it knocked off the Pittsburgh Maulers 17-3. The Bandits are 2.5-point favorites in the latest Week 2 USFL odds from Caesars Sportsbook, and the over-under is 40.5. Every one of the Week 2 USFL spreads is under seven points, so this is expected to be another highly-competitive slate of games. All of the Week 2 USFL lines are listed below, and SportsLine pro football expert, R.J. White, has all the USFL betting advice and predictions you need to make the best Week 2 USFL picks now.

CBS Sports' Fantasy and gambling managing editor, White has delivered consistently on a high volume of picks over the long-term, returning $2,542 to $100 bettors on more than 800 against the spread picks since the start of the 2017 NFL season. It's no surprise, as White has cashed huge twice in the world's most prestigious football handicapping competition, the Las Vegas SuperContest.

He was also 16-4 on all XFL ATS picks before the league suspended operations in 2020. That included starting a 13-1 run at the start as books scrambled to correctly evaluate team quality in a league where little was known heading into the season. He also had a successful opening week for the 2022 USFL season, going 3-1 with his USFL picks. If anybody can spot value in the USFL lines, it's him.

Now, White has turned its attention to the latest Week 2 USFL odds from Caesars and locked in picks for every USFL matchup. Head here to see every pick.

Top Week 2 USFL predictions

One of the top Week 2 USFL predictions White recommends: The New Orleans Breakers (+2.5) cover against the Bandits on Sunday. These may end up being the best two teams in the league and both pitched strong defensive efforts in their Week 1 victories. But New Orleans' offense showed much more potential in the opener, specifically with its multi-dimensional backfield.

Tampa, and perhaps every USFL team, will have problems containing the Breakers' two-headed rushing attack. Jordan Ellis led New Orleans with 89 yards and a touchdown on the ground last week, averaging a robust 4.9 yards per carry. Fellow RB T.J. Logan -- who owns a Super Bowl ring as a member of the 2020 Tampa Bay Buccaneers -- contributed 94 scrimmage yards and also found the endzone. The Breakers rank second in the USFL in yards per carry and their productivity on the ground will keep Tampa QB Jordan Ta'amu on the sideline.

Keeping Ta'amu on the sideline may actually be beneficial for the Bandits after the former Ole Miss star struggled mightily in the opener. He was the only USFL quarterback to throw two interceptions and was a non-factor on the ground, rushing for just seven yards. White foresees more headaches for Tampa's offense going up against what could be the league's best defense.

"In a few weeks, I'd give the Bandits the edge here once their offense is in rhythm," White told SportsLine. "But right now, I think the Breakers' high-level defense helps secure the win, and it's possible the Bandits defense isn't as good as they looked last week."

Make Week 2 USFL picks 

White has also made the call on who wins and covers in every other game on the Week 2 USFL schedule, and he's predicting another favorite to go down hard. You can only get every pick for every game at SportsLine.

So what USFL picks can you make with confidence? And which favorite goes down hard? Check out the latest USFL odds below, then visit SportsLine to see which teams win and cover the spread, all from the pro football expert that went 16-4 on all XFL ATS picks and is 3-1 on USFL predictions, and find out.

Week 2 USFL schedule, odds (via Caesars)

Saturday, April 23

12:05 ET Pittsburgh Maulers at Philadelphia Stars (-6, 36)

7:05 p.m. ET Birmingham Stallions at Houston Gamblers (+3, 41)

Sunday, April 24

3:05 p.m. ET New Orleans Breakers at Tampa Bay Bandits (-2.5, 40.5)