NFL odds, lines, picks, spreads, best bets, predictions, office pool, best survivor picks for Week 8, 2022

USATSI

The Philadelphia Eagles are the only team with an unblemished record entering the Week 8 NFL schedule. However, the Eagles will need to keep winning if they want to stay atop the NFC West standings after the Giants (6-1) and Cowboys (5-2) continued their strong starts to the season. Philadelphia will host the Pittsburgh Steelers at 1 p.m. ET on Sunday. According to the latest Week 8 NFL odds from Caesars Sportsbook, the Eagles are 11-point favorites in their in-state rival. Other notable Week 8 NFL spreads include 49ers vs. Rams (+1.5), Giants vs. Seahawks (-3) and Packers vs. Bills (-11). Which NFL Vegas odds, NFL totals and NFL money lines should you target in your Week 8 NFL bets? All of the Week 8 NFL lines are listed below, and SportsLine's advanced computer model has all the NFL betting advice and predictions you need to make the best Week 8 NFL picks now.

The model, which simulates every NFL game 10,000 times, is up almost $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 8 of the 2022 NFL season on an incredible 148-107 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, it has turned its attention to the latest Week 8 NFL odds and locked in picks for every NFL matchup. Head here to see every pick.

Top Week 8 NFL predictions

One of the model's strongest Week 8 NFL picks is that the Colts (-3) cover the spread at home against Washington. After throwing nine interceptions, being sacked 24 times and fumbling a league-worst 11 times, Matt Ryan has been benched by the Colts in favor of former Texas star Sam Ehlinger. He threw for 11,446 yards and 94 touchdowns during his career at Texas and also rushed for 1,903 yards and 33 scores.

The sixth-round pick in the 2021 NFL Draft played in three games as a rookie and will get his first career start against a Washington defense that has had issues with dual-threat quarterbacks. Jalen Hurts threw for 340 yards and three touchdowns while adding 20 yards on the ground in Week 3 and Justin Fields threw for 190 yards and a touchdown while rushing for 88 yards back in Week 6.

Jonathan Taylor will also be another week healthier after touching the ball 17 times in his return from an ankle injury that sidelined him for a game. The model is predicting that Taylor piles up nearly 100 yards on the ground and that Ehlinger has an effective day, throwing for 216 yards, two touchdowns and an interception on average. That helps the Colts cover the spread in well over 50 percent of simulations. See which other teams to pick here.

Top Week 8 NFL survivor picks

The model's Week 8 NFL knockout pool picks say to avoid the Raiders, even though they are road favorites over the Saints. New Orleans enters Sunday's showdown with a 2-5 record, but they're still in the hunt to win the NFC South.

Despite underperforming this season, New Orleans features one of the league's most potent offenses. The Saints are averaging 398.3 yards per game, which ranks third. Quarterback Andy Dalton threw for 361 yards and four touchdowns in New Orleans' loss against the Cardinals and will now look to dissect a Las Vegas defense that's giving up 366.7 yards per game. There are just too many factors going against the Raiders, so the model says to steer clear of them for Week 8 NFL survivor picks despite Las Vegas being the favorite. See which team you should pick here.

Top Week 8 NFL office pool picks

One of the strongest Week 8 NFL football pool picks from the model is that the Titans beat the Texans. Tennessee has as much momentum as any team after opening the season with a pair of disappointing losses. The Titans have responded with a four-game winning streak, including a 19-10 win against Indianapolis last week. They have a chance to take firmer control of the AFC South on Sunday, so they will be motivated heading into this contest.

Houston has only picked up one win this season and is coming off a blowout loss at Las Vegas. The Texans lost to the Chargers by double digits in their last home game and have failed to score more than 24 points in a game this season. Tennessee's defense has only allowed more than 21 points on one occasion, which came against the Bills in Week 2. Tennessee's Derrick Henry is projected to rush for more than 100 yards, which is one reason why the Titans are winning outright 60% of the time. See which other teams to pick here.

How to make Week 8 NFL picks

The model has also made the call on who wins and covers in every other game on the Week 8 NFL schedule, and it also says a Super Bowl contender goes down hard. It's also backing a shocking team in its NFL survivor picks. You can only get every pick for every game at SportsLine.

So what NFL predictions, NFL pool picks, and NFL survivor picks can you make with confidence? And which Super Bowl contender goes down hard? Check out the latest NFL odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned almost $7,000 since its inception, and find out.