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Big Ten foes collide on Saturday evening when No. 3 Ohio State (3-0) and Wisconsin (2-1) match up. Both teams roll into this contest with exciting and explosive offenses. Ohio State ranks third in the Big Ten in scoring (47.7 ppg) while Wisconsin is sixth (39.3). Ohio State has scored 45-plus in two games. Meanwhile, Wisconsin has also dropped 38-plus points in two of its three games played.

Kickoff from Ohio Stadium is set for 7:30 p.m. ET. Caesars Sportsbook lists the Buckeyes at -19 in the latest Ohio State vs. Wisconsin odds, while the over/under for total points is set at 56.5. Before finalizing any Wisconsin vs. Ohio State picks, be sure to check out the college football predictions and betting advice from SportsLine's proven model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of more than $3,300 for $100 players on its top-rated college football picks against the spread. It enters Week 4 of the 2022 college football season on a 51-43 run on all top-rated college football spread and money-line picks that dates back to 2021. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Wisconsin vs. Ohio State and just revealed its picks and predictions. You can visit SportsLine now to see the model's picks. Now, here are several college football odds and betting lines for Ohio State vs. Wisconsin:

  • Ohio State vs. Wisconsin spread: Buckeyes -19
  • Ohio State vs. Wisconsin over/under: 56.5 points  
  • Ohio State vs. Wisconsin money line: Buckeyes -1100, Badgers +700 
  • OSU: Over is 9-4-1 in Buckeyes' last 14 conference games 
  • WIS: Badgers are 5-2 ATS in their last seven conference games 
  • Ohio State vs. Wisconsin picks: See picks here
Featured Game | Ohio State Buckeyes vs. Wisconsin Badgers

Why Ohio State can cover

The Buckeyes have several impressive backs. Each running back provides a different element to the ground attack. This group averages 207 rushing yards per game which rank sixth in the Big Ten. Junior running back Miyan Williams is a physical tailback who stays low to the ground. Williams runs with violence and is able to barrel through defenders. The Ohio native leads the team with 32 carries for 207 yards with 6.5 yards per carry. Last week, he finished with 10 carries for 77 yards.

Sophomore running back TreVeyon Henderson has excellent speed with superb vision and patience. Henderson shows good contact balance and moves to evade defenders. The Virginia native is second on the squad in carries (29) and rushing yards (197) while leading the team in rushing touchdowns (3). In Week 2, he had 10 carries for 87 yards with two scores. 

Why Wisconsin can cover

The Badgers have a solid all-around defensive unit. Teams haven't been able to consistently move the ball against the Badgers and Wisconsin is looking to bring that momentum into this game. They are ranked fifth in the Big Ten in total yards allowed (246), third in rushing yards (76  and fourth in passing yards (170). Junior linebacker Maema Njongmeta is an instinctive defender who is always around the ball.

Njongmeta is a stout run defender and flies from sideline to sideline. The Illinois native is first on the team in total tackles (19) including 12 solo. Safety John Torchio has great awareness in coverage and gets his hands on the ball. Torchio makes plays in both the run and pass game. He is second on the team in total stops (11) including a 100-yard interception return for a score. 

How to make Wisconsin vs. Ohio State picks

SportsLine's model is leaning Under on the total, projecting the teams to combine for 50 points. The model also says one side of the spread hits in well over 60% of simulations. You can only get the model's pick at SportsLine

So who wins Wisconsin vs. Ohio State? And which side of the spread hits in well over 50% of simulations? Visit SportsLine now to see which side of the spread you need to jump on, all from the model that has crushed its college football picks, and find out.