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The latest chapter in one of college football's oldest rivalries will be written on Saturday, November 27 when the No. 11 Oregon Ducks (9-2) host the Oregon State Beavers (7-4) at Autzen Stadium in Eugene, Ore.. Oregon is coming off a highly disappointing 38-7 loss to No. 19 Utah that knocked the Ducks out of College Football Playoff contention. The Beavers enter this week on a two-game winning streak after knocking off Arizona State 24-10 last Saturday. Oregon State is 7-4, while Oregon is 4-7 against the spread in 2021.

Kickoff is at 3:30 p.m. ET. The Ducks are favored by seven points in the latest Oregon vs. Oregon State odds from Caesars Sportsbook, and the over-under is set at 61.5. Before making any Oregon State vs. Oregon picks, you need to check out the college football predictions and betting advice from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,700 for $100 players on its top-rated college football picks against the spread. It also enters Week 13 of the 2021 season on a 39-25 run on all top-rated college football side picks. Anyone who has followed it has seen huge returns.

Now, the model has locked in on Oregon vs. Oregon State and just revealed its CFB picks and predictions. You can head to SportsLine now to see the model's picks. Here are several college football odds and betting lines for Oregon vs. Oregon State:

  • Oregon vs. Oregon State spread: Oregon -7
  • Oregon vs. Oregon State over-under: 62 points
  • Oregon vs. Oregon State moneyline: Oregon -280, Oregon State +230
Featured Game | Oregon Ducks vs. Oregon State Beavers

What you need to know about Oregon

Oregon has to be hurting after a devastating 38-7 loss at the hands of the Utah Utes on Saturday. Oregon was in a tough position by the half, with the score already sitting at 28-0. The loss knocked the Ducks out of CFP contention, but they can clinch a spot in the Pac-12 Championship Game and a rematch against Utah with a trip to the Rose Bowl on the line if they can notch a win over Oregon State this week. 

The Ducks' offensive issues were apparent against Utah. They should find smoother sailing against Oregon State, but there is no telling what will happen in a bitter rivalry game such as this. Look for Oregon to lean heavily on its 1-2 punch of Travis Dye and Byron Cardwell at running back. The Ducks have two legitimate stars on defense in Kayvon Thibodeaux and Noah Sewell

What you need to know about Oregon State

Meanwhile, the Arizona State Sun Devils typically have all the answers at home, but on Saturday Oregon State proved too difficult a challenge. The Beavers beat the Sun Devils 24-10. The team accrued 17 points in the first half and coasted on those for the win. Oregon State's RB B.J. Baylor was stellar, racking up 150 yards on the ground on 20 carries.

Oregon State has already locked up its first winning season since 2013. The Beavers have had some offensive issues in 2021, but they have settled in nicely with Chance Nolan at quarterback. OSU's defense has been one of the Pac-12's best, but the Ducks, despite their own offensive struggles, will present some challenges. If the Beavers can neutralize Thibodeaux and Sewell, they will have a good shot at pulling off the upset here. 

How to make Oregon vs. Oregon State picks

The model has simulated Oregon vs. Oregon State 10,000 times and the results are in. We can tell you that the model is leaning Under on the point total, and it's also generated a point-spread pick that is hitting in almost 60 percent of simulations. You can only see the model's Oregon vs. Oregon State pick at SportsLine.

So who wins Oregon State vs. Oregon? And which side of the spread hits in almost 60 percent of simulations? Visit SportsLine now to see which side of the Oregon vs. Oregon State spread you need to jump on, all from the model that has crushed its college football picks, and find out.