The Rutgers Scarlet Knights and the Northwestern Wildcats will face off in a Big Ten battle at 12 p.m. ET on Saturday at Ryan Field. The Wildcats are 2-3 overall and 2-1 at home, while Rutgers is 3-3 overall and 1-1 on the road. These teams have played once before since Rutgers joined the Big Ten and the Wildcats prevailed in that 2018 matchup.

The Scarlet Knights are favored by two points in the latest Rutgers vs. Northwestern odds, and the over-under is set at 45. Before entering any Northwestern vs. Rutgers picks, you'll want to see the college football predictions from the proven computer model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,800 for $100 players on its top-rated college football picks against the spread. It also enters Week 7 of the 2021 season on a 19-7 run on all top-rated college football side picks. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Rutgers vs. Northwestern. You can head to SportsLine to see its picks. Here are several college football odds for Northwestern vs. Rutgers:

  • Northwestern vs. Rutgers spread: Rutgers -2
  • Northwestern vs. Rutgers: over-under: 45 points

What you need to know about Rutgers

For the Scarlet Knights, 13 has been an unlucky number as the team has scored exactly 13 points in its last three games -- all losses. They eclipsed 13 points in each of their first three contests and those were all wins. Rutgers will get a slight reprieve in facing the unranked Northwestern Wildcats on Saturday as its previous three opponents were all ranked in the top 20.

As such, Rutgers has the third hardest strength of schedule in all of FBS. While Greg Schiano's unit on offense has struggled to find the endzone, the Scarlet Knights' defense has been stout. Rutgers has allowed 20 or fewer points in four games this season and gone 3-1 in those contests.

What you need to know about Northwestern

The Wildcats have alternated losses and wins this season and most of the games haven't even been close. Only one of their five games has been decided by fewer than 17 points as Northwestern has won big and lost big. It is coming off a 49-point loss to Nebraska, so the Northwestern faithful are hoping the trend of alternating results continues on Saturday.

Northwestern's offense revolves around RB Evan Hull, who has 509 rushing yards and four touchdowns. He ranks second in the Big Ten with 7.3 yards per attempt and is sixth with 571 yards from scrimmage. As he goes, the team goes as Hull averages 171 rushing yards in Northwestern's wins and 56 yards in its losses.

How to make Northwestern vs. Rutgers picks

The model has simulated Rutgers vs. Northwestern 10,000 times and the results are in. We can tell you that the model is leaning under, and it's also generated a point-spread pick that hits in over 50 percent of simulations. You can only see the pick at SportsLine.

So who wins Northwestern vs. Rutgers? And which side of the spread hits over 50 percent of the time? Visit SportsLine now to find out which side of the spread you need to jump on, all from the model that has crushed its college football picks, and find out.