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Thankfully, there aren't too many injuries to worry about at quarterback for Week 16. Matthew Stafford (ribs) and Derek Carr (groin) are the biggest question marks but it's not like many people were really going to be starting either in their championship game. Which means your start and sit decisions are mostly going to come down to who the best player is. And that's the way we want it to go in Week 16. 

Get help with your toughest decisions at quarterback with Jamey Eisenberg's Start 'Em & Sit 'Em calls below, and if you need help at running back you can head here:  

More Week 16: Start 'Em & Sit 'Em: QB | Start 'Em & Sit 'Em: RB | Start 'Em & Sit 'Em: WRWaiver Wire | QB Preview | RB Preview | WR Preview | TE Preview | Who Can You Trust?      

START 'EM & SIT 'EM
Quarterbacks
Start 'Em
Projections powered by Sportsline
PHI Philadelphia • #1
Age: 23 • Experience: 3 yrs.
Weekly Breakdown
MATCHUP
@ DAL PHI -2.5 O/U 49.5
OPP VS QB
24th
PROJ PTS
25.9
QB RNK
5th
YTD Stats
PAYDS
647
RUYDS
254
TD
6
INT
1
FPTS/G
6.5
For those of you who picked up Hurts over the past three weeks and advanced to your Fantasy championship (or semifinals if you play into Week 17), you know to start him. That's obvious, and a Fantasy analyst doesn't need to explain that to you. But it's who you're starting him over that matters, and for me it's everyone not named Mahomes, Rodgers, Allen or Murray. And even the latter two are questionable, especially if Stefon Diggs (foot) is out for the Bills. Hurts has 63 Fantasy points in his past two games, with 269 rushing yards and a touchdown over that span and a great matchup against Dallas in Week 16. The Cowboys have allowed at least 24 Fantasy points to opposing quarterbacks in four of their past six games.
TB Tampa Bay • #12
Age: 44 • Experience: 23 yrs.
Weekly Breakdown
MATCHUP
@ DET TB -9.5 O/U 54
OPP VS QB
29th
PROJ PTS
27.2
QB RNK
8th
YTD Stats
PAYDS
3886
RUYDS
3
TD
35
INT
11
FPTS/G
24.4
Brady got off to a slow start in Week 15 at Atlanta, but he finished strong with 390 passing yards and two touchdowns. He's now scored at least 23 Fantasy points in four road games in a row, and the Lions have allowed three of their past four opposing quarterbacks to score at least 36 Fantasy points. For the season, Detroit allows 25.4 Fantasy points to opposing quarterbacks, and Brady should be locked in as a top-10 Fantasy passer this week.
LAC L.A. Chargers • #10
Age: 24 • Experience: 3 yrs.
Weekly Breakdown
MATCHUP
vs DEN LAC -3 O/U 48.5
OPP VS QB
20th
PROJ PTS
24.9
QB RNK
9th
YTD Stats
PAYDS
3781
RUYDS
199
TD
31
INT
10
FPTS/G
25.9
After a three-game lull where Herbert scored 19 Fantasy points or less, he was back to being a star in Week 15 at the Raiders with 31 points. He did that with Keenan Allen and Mike Williams at less than 100%, and hopefully both are back to full strength this week against the Broncos. Herbert had 27 Fantasy points at Denver in Week 8, and the Broncos have allowed three quarterbacks in a row to score at least 20 Fantasy points, including Josh Allen scoring 41 points last week. Herbert also likes playing at home since he's averaging 23.5 Fantasy points in seven games in Los Angeles this year.
TEN Tennessee • #17
Age: 33 • Experience: 11 year
Weekly Breakdown
MATCHUP
@ GB GB -3.5 O/U 56
OPP VS QB
8th
PROJ PTS
21.7
QB RNK
10th
YTD Stats
PAYDS
3482
RUYDS
173
TD
35
INT
5
FPTS/G
25.8
This isn't an easy matchup for Tannehill since the Packers only allow 18.4 Fantasy points per game to opposing quarterbacks, and three quarterbacks in a row have scored 16 Fantasy points or fewer. But I'm going to stick with Tannehill as a top-10 Fantasy quarterback in all leagues, as he's averaging 28.0 Fantasy points per game in his past five outings. If he's forced to chase points this week at Green Bay then he could have a similar performance to what we saw in Week 13 against Cleveland when he completed 29-of-45 passes for 389 yards, three touchdowns and one interception, and he scored 33 Fantasy points in that matchup.
NO New Orleans • #9
Age: 43 • Experience: 20 yrs.
Weekly Breakdown
MATCHUP
vs MIN NO -7 O/U 51
OPP VS QB
14th
PROJ PTS
21.4
QB RNK
12th
YTD Stats
PAYDS
2430
RUYDS
1
TD
23
INT
4
FPTS/G
22.4
Brees returned from his four-game absence with a rib injury in Week 15 against the Chiefs and scored 25 Fantasy points. That's now five games in a row that he's finished and scored at least 23 Fantasy points, and I expect him to be in that range again in Week 16 against the Vikings. While it's not an easy matchup since Minnesota has held four quarterbacks in a row to 19 Fantasy points or fewer, I'll trust Brees' track record at home -- he's averaging 24.4 Fantasy points per game in five healthy games in New Orleans this year -- and his need to get in a rhythm prior to the playoffs. He should be considered a low-end starter in all leagues.
Sleepers
Projections powered by Sportsline
CLE Cleveland • #6
Age: 27 • Experience: 5 yrs.
Weekly Breakdown
MATCHUP
@ NYJ CLE -9.5 O/U 47
OPP VS QB
30th
PROJ PTS
20.2
QB RNK
13th
YTD Stats
PAYDS
3082
RUYDS
115
TD
26
INT
8
FPTS/G
19.6
Mayfield has been amazing over the past four games, and he should stay hot this week against the Jets. He's scored at least 22 Fantasy points in four games in a row, and he's averaging 28.8 points over that span. The Jets held Jared Goff to 18 Fantasy points in Week 15, but prior to that six quarterbacks in a row scored at least 23 points.
PIT Pittsburgh • #10
Age: 27 • Experience: 6 yrs.
Weekly Breakdown
MATCHUP
@ JAC CHI -7.5 O/U 47.5
OPP VS QB
31st
PROJ PTS
21.5
QB RNK
11th
YTD Stats
PAYDS
1538
RUYDS
163
TD
14
INT
6
FPTS/G
18.4
Trubisky is playing surprisingly well over the past four games after regaining his starting job from Nick Foles, and he should have the chance for another quality Fantasy outing in Week 16 against the Jaguars, who have allowed eight quarterbacks in a row to score at least 20 Fantasy points. Trubisky has at least 24 Fantasy points in two of his past four outings.
MIA Miami • #1
Age: 24 • Experience: 3 yrs.
Weekly Breakdown
MATCHUP
@ LV MIA -3 O/U 47.5
OPP VS QB
22nd
PROJ PTS
23.7
QB RNK
16th
YTD Stats
PAYDS
1359
RUYDS
70
TD
12
INT
2
FPTS/G
16.2
Tagovailoa only has two games with more than 18 Fantasy points as a starter, but he could be useful this week in deeper leagues with his matchup against the Raiders, who have allowed three quarterbacks in a row to score at least 21 Fantasy points. It would help Tagovailoa if DeVante Parker (hamstring) and Mike Gesicki (shoulder) return from their injuries this week, and Tagovailoa also has three rushing touchdowns in his past two games.
Sit 'Em
Projections powered by Sportsline
PIT Pittsburgh • #7
Age: 40 • Experience: 18 yrs.
Weekly Breakdown
MATCHUP
vs IND IND -1.5 O/U 44.5
OPP VS QB
6th
PROJ PTS
16.5
QB RNK
19th
YTD Stats
PAYDS
3462
RUYDS
12
TD
30
INT
10
FPTS/G
21.6
Things have been unraveling for Roethlisberger over the past few weeks, and he hit rock bottom with his Fantasy production in Week 15 at Cincinnati, scoring a season-low eight points. He's now scored 17 Fantasy points or fewer in three of his past four starts, and it's impossible to trust him in Week 16 against the Colts. While Indianapolis has allowed four of the past five opposing quarterbacks to score at least 20 Fantasy points, this is more about Roethlisberger and less about his opponent. You can't start him with any level of confidence in Week 16.
MIN Minnesota • #8
Age: 33 • Experience: 11 year
Weekly Breakdown
MATCHUP
@ NO NO -7 O/U 51
OPP VS QB
9th
PROJ PTS
15.9
QB RNK
20th
YTD Stats
PAYDS
3569
RUYDS
155
TD
29
INT
13
FPTS/G
21.9
In his last road game in Week 14 at Tampa Bay, Cousins scored 19 Fantasy points. That pushed his average on the road this season up to 13.8 Fantasy points per game. This is not a good spot to trust Cousins, and the Saints are allowing just 19.3 Fantasy points per game to opposing quarterbacks this year. I would only start Cousins in two-quarterback and Superflex leagues this week.
IND Indianapolis • #17
Age: 40 • Experience: 17 yrs.
Weekly Breakdown
MATCHUP
@ PIT IND -1.5 O/U 44.5
OPP VS QB
2nd
PROJ PTS
15.7
QB RNK
23rd
YTD Stats
PAYDS
3735
RUYDS
-6
TD
22
INT
9
FPTS/G
18.8
Rivers has been solid of late with at least 21 Fantasy points in each of his past five games, but I'd be hesitant to start him this week at Pittsburgh. While the Steelers offense has struggled, the defense has still been excellent, and only Josh Allen in Week 14 has more than 19 Fantasy points against Pittsburgh since Week 7. For the season, the Steelers allow just 16.3 Fantasy points per game to opposing quarterbacks, and Rivers will likely have his five-game streak of scoring at least 21 Fantasy points snapped in this matchup.
LV Las Vegas • #4
Age: 31 • Experience: 9 yrs.
Weekly Breakdown
MATCHUP
vs MIA MIA -3 O/U 47.5
OPP VS QB
4th
PROJ PTS
18.5
QB RNK
21st
YTD Stats
PAYDS
3396
RUYDS
141
TD
26
INT
7
FPTS/G
19.7
Carr is expected to play against the Dolphins despite hurting his groin in Week 15 against the Chargers, and hopefully he's good for Darren Waller and those of you starting Nelson Agholor. But as for Carr's Fantasy value, he should only be considered in two-quarterback and Superflex leagues. While he did score at least 27 Fantasy points in his two previous starts prior to Week 15 against the Jets and Colts, this Dolphins defense is legit. Only one opposing quarterback in their past six games has more than 11 Fantasy points, which was Patrick Mahomes in Week 14, and he only scored 21 points since he had three interceptions. For the season, Miami allows just 17.6 Fantasy points per game to opposing quarterbacks.
LAR L.A. Rams • #9
Age: 34 • Experience: 14 yrs.
Weekly Breakdown
MATCHUP
vs TB TB -9.5 O/U 54
OPP VS QB
21st
PROJ PTS
17.4
QB RNK
17th
YTD Stats
PAYDS
3774
RUYDS
103
TD
23
INT
9
FPTS/G
20.2
Stafford is playing through his rib injury, but he's clearly not 100%. He played in Week 15 at Tennessee and completed 22-of-32 passes for 252 yards and one touchdown, and he added 12 rushing yards. He only has one game with more than 17 Fantasy points in his past five outings, and the Buccaneers should make things uncomfortable for him with his injury. If he was 100 percent then he would be a low-end starting option this week, but since he's hurt -- and without Kenny Golladay (hip) again -- it should be easy to avoid Stafford in most one-quarterback formats.
Bust Alert
Projections powered by Sportsline
DEN Denver • #3
Age: 33 • Experience: 11 year
Weekly Breakdown
MATCHUP
vs LAR SEA -1.5 O/U 47.5
OPP VS QB
1st
PROJ PTS
22.2
QB RNK
14th
YTD Stats
PAYDS
3806
RUYDS
475
TD
38
INT
13
FPTS/G
28.2
Wilson scored nine Fantasy points against the Rams in Week 10, and he's been at 16 Fantasy points or less in three of his past four starts. He went from an elite Fantasy quarterback to a question mark, and it's hard to count on him this week. The Rams allow just 14.3 Fantasy points per game to opposing quarterbacks, and only Josh Allen in Week 3, Jimmy Garoppolo in Week 6 and Kyler Murray in Week 13 have scored more than 19 Fantasy points against Los Angeles. Consider Wilson a low-end starting option at best this week, but he's someone I would prefer to avoid.

So who should you start and sit this week? And which surprising quarterback could lead you to victory? Visit SportsLine now to get Week 15 rankings for every position, plus see which QB is going to come out of nowhere to crack the top 10, all from the model that out-performed experts big-time last season.