The Baylor Bears attempt to hand the No. 4 TCU Horned Frogs their first loss of the season when they host their Big 12 rivals on Saturday. Baylor (6-4, 4-3 Big 12) has not fared well in the all-time series of late, losing six of the last seven meetings. The Bears enter this year's matchup on the heels of a 31-3 setback against 19th-ranked Kansas State. TCU (10-0, 7-0), which is seeking the third perfect season in school history and first since 2010, posted a 17-10 victory at then-No. 18 Texas last week.

Kickoff at McLane Stadium in Waco, Tex.is set for noon ET. The Horned Frogs are 2-point favorites in the latest TCU vs. Baylor odds from Caesars Sportsbook, while the over/under for total points scored is 57. Before making any Baylor vs. TCU picks, you need to see the college football predictions and betting advice from SportsLine's advanced computer model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on TCU vs. Baylor and locked in its picks and CFB predictions. You can head to SportsLine now to see the model's picks. Here are several college football odds and betting lines for Baylor vs. TCU:

  • TCU vs. Baylor spread: Horned Frogs -2
  • TCU vs. Baylor over/under: 57 points
  • TCU vs. Baylor money line: Horned Frogs -135, Bears +115
  • TCU: The Horned Frogs are 8-2 against the spread in their last 10 meetings with Baylor
  • BAY: The Bears are 22-8 ATS in their last 30 games against teams with winning records
  • TCU vs. Baylor picks: See picks at SportsLine
Featured Game | Baylor Bears vs. TCU Horned Frogs

Why TCU can cover

The Horned Frogs own a 57-53-7 record in the all-time series and have actually had more success on the road, where they've gone 29-24-1 as opposed to 28-29-4 at home. TCU has won six of the last seven overall meetings, with the only loss during that span coming in triple overtime in 2019. It has performed well of late offensively, scoring at least 30 points in four of its last five victories against the Bears.

TCU is becoming known for big plays as it is first in the nation with 15 that have gone for at least 50 yards. The Horned Frogs also are No. 1 in the FBS with nine plays of 60 or more yards and lead all Power 5 schools with 13 touchdowns of 50 or more yards while senior Max Duggan ranks first among Power 5 quarterbacks with 15 TD passes of at least 20 yards. Junior running back Kendre Miller has posted five straight 100-yard performances, the program's longest streak since Lonta Hobbs had a five-gamer in 2002, and has run for at least one touchdown in every contest this year.

Why Baylor can cover

Despite having lost two of their last three home games, the Bears have performed well at McLane Stadium under head coach Dave Aranda, going 12-4 there since the start of the 2020 season. They'll be looking for a bounce-back effort from Richard Reese, who has rushed for only 61 yards over his last two games after recording back-to-back 100-yard performances. He is one of the most productive freshman running backs in the country as he ranks second in both rushing yards (852) and touchdowns (13).

Reese is 30 yards away from breaking the school record for most by a freshman, which was set in 2013 by Shock Linwood. The Bears have another dangerous rusher in Craig Williams, who came up with a huge performance in a 38-35 at Oklahoma two weeks ago. The junior entered the contest with 456 yards over 13 games in his injury-plagued career but gained a whopping 192 yards on 25 carries, including two for touchdowns against the Sooners.

How to make Baylor vs. TCU picks

SportsLine's model is leaning Over on the total, projecting a combined 63 points. The model also says one side of the spread hits in 60% of simulations. You can only see the model's CFB picks at SportsLine.

So who wins TCU vs. Baylor? And which side of the spread hits in 60% of simulations? Visit SportsLine now to see which side of the spread you need to jump on, all from the model that has crushed its college football picks, and find out.