The Missouri Tigers and the Ole Miss Rebels are set to square off in a 2022 SEC Tournament matchup at 6 p.m. ET on Wednesday at Amalie Arena. Ole Miss is 13-18 overall, while the Tigers are 11-20. Missouri swept the regular-season series between these teams. 

The Rebels are favored by 3.5 points in the latest Missouri vs. Ole Miss odds from Caesars Sportsbook, while the over-under is set at 131.5. Before entering any Ole Miss vs. Missouri picks, you'll want to see the college basketball predictions from the proven computer model at SportsLine.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $1,600 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Missouri vs. Ole Miss. You can head to SportsLine to see its picks. Here are several college basketball odds for Missouri vs. Ole Miss:

  • Missouri vs. Ole Miss spread: Missouri +3.5
  • Missouri vs. Ole Miss over-under: 131.5 points
Featured Game | Missouri Tigers vs. Ole Miss Rebels

What you need to know about Missouri

Missouri was on a six-game losing streak heading into its regular-season finale against Georgia. The Tigers were able to snap out of their funk with a 79-69 win over the Bulldogs last Saturday. They will now be aiming for their third win over Ole Miss this season. 

The Tigers shot 62.7 percent from the floor in a 78-53 win in the first meeting and they shot 53.8 percent in a 74-68 win in the rematch. Junior forward Kobe Brown leads Missouri with 12.6 points and 7.8 rebounds per game, while senior guard Javon Pickett is adding 11.1 points. The Tigers have only covered the spread twice in their last seven games as underdogs. 

What you need to know about Ole Miss

Ole Miss has been one of the most disappointing teams in the conference this season, closing the year on a four-game losing streak. The Rebels came up just short in a 63-61 final against Vanderbilt on Saturday. They were without leading scorer Jarkel Joiner in the first loss to Missouri, but he scored 13 points and grabbed four rebounds in the rematch. 

Joiner was held to just two points in the loss to Vanderbilt, dropping his average to 13.2 points per game. The Rebels have been without second-leading scorer Daeshun Ruffin for most of the season due to a season-ending injury. Ole Miss has covered the spread in six of its last nine games against Missouri. 

How to make Missouri vs. Ole Miss picks

The model has simulated Missouri vs. Ole Miss 10,000 times and the results are in. We can tell you that the model is leaning over, and it also says one side of the spread has all the value. You can only see the pick at SportsLine.

So who wins Ole Miss vs. Missouri? And which side of the spread has all the value? Visit SportsLine now to find out, all from the model that has crushed its college basketball picks.