The No. 5 Tennessee Volunteers will try to keep themselves in the thick of the College Football Playoff race when they face the South Carolina Gamecocks on Saturday night. Tennessee recovered from its first loss of the season by blowing out Missouri last week, maintaining its position in the latest rankings. South Carolina is hoping to play spoiler after losing to Florida in a 38-6 final its last time out.

Kickoff is set for 7 p.m. ET. The Vols are currently listed as 22-point favorites in the latest Tennessee vs. South Carolina odds from Caesars Sportsbook, while the over/under for total points scored is 66. Before entering any South Carolina vs. Tennessee picks, you'll want to see the college football predictions from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on South Carolina vs. Tennessee. You can head to SportsLine to see its picks. Here are several college football odds for Tennessee vs. South Carolina:

  • Tennessee vs. South Carolina spread: Tennessee -22
  • Tennessee vs. South Carolina over/under: 66 points
  • Tennessee vs. South Carolina money line: South Carolina +1050, Tennessee -2000
  • Tennessee vs. South Carolina picks: See picks here
Featured Game | South Carolina Gamecocks vs. Tennessee Volunteers

Why South Carolina can cover

South Carolina has dealt with inconsistency at times this season, but it has won five of its last seven games. The Gamecocks recorded consecutive wins against then-No. 13 Kentucky and Texas A&M, so they are capable of hanging around against quality opponents. They have been without leading rusher MarShawn Lloyd the past two games due to a bruised thigh and he's been ruled out for this one as well.

Quarterback Spencer Rattler has thrown for 1,982 yards and eight touchdowns, finding junior wide receiver Antwane Wells Jr. 43 times for 590 yards and four scores. South Carolina is 8-3 in its last 11 home games, so this is not an easy place for opposing teams to visit. 

Why Tennessee can cover

Tennessee is currently outside of the College Football Playoff picture, so it is looking to win with margin on Saturday night. The Vols have covered the spread at a 6-3-1 clip in the last 10 meetings between these teams, including a 45-20 win last season. They have also covered the spread in eight of their 10 games this year, so the betting market has not adjusted to how well Tennessee is playing.

Senior quarterback Hendon Hooker is near the top of the Heisman Trophy race, throwing for 2,888 yards and 24 touchdowns. He has also rushed for 405 yards and five scores, headlining an offense that leads the nation in scoring offense and total offense. South Carolina has already been blown out multiple times this year and has only covered the spread twice in its last 12 home games against Tennessee. 

How to make South Carolina vs. Tennessee picks

The model has simulated Tennessee vs. South Carolina 10,000 times and the results are in. The model is leaning Under, and it's also generated a point-spread pick that is hitting in well over 50% of simulations. You can only see the pick at SportsLine.

So who wins South Carolina vs. Tennessee? And which side of the spread hits in well over 50% of simulations? Visit SportsLine now to see which side of the Tennessee vs. South Carolina spread you need to jump on Saturday, all from the model that has crushed its college football picks, and find out.