The Boston Celtics (36-15) are hosting the Brooklyn Nets (31-19) in an Eastern Conference collision on Wednesday night. The Celtics are currently first in the East, while Brooklyn sits as the fourth seed. Boston won both previous matchups this season and owns a five-game win streak over Brooklyn. Marcus Smart (ankle) is out for Boston with Robert Williams III (ankle) listed as questionable. Kevin Durant (knee) remains out for Brooklyn, while Ben Simmons (knee) and T.J. Warren (shin) are also sidelined for the Nets.

Tip-off is scheduled for 7:30 p.m. ET at TD Garden in Boston. Caesars Sportsbook lists the Celtics as a 9-point home favorite in the latest Celtics vs. Nets odds, while the over/under for total points scored is set at 224. Before making any Nets vs. Celtics picks, you'll want to see the NBA predictions and betting advice from the proven computer model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past four-plus seasons. The model enters Week 16 of the 2022-23 NBA season on a stunning 49-23 roll on all top-rated NBA picks this season, returning nearly $2,300. Anyone following it has seen huge returns.

Now, the model has set its sights on Nets vs. Celtics and just locked in its picks and NBA predictions. You can head to SportsLine now to see the model's picks. Here are several NBA betting lines and trends for Celtics vs. Nets:

  • Nets vs. Celtics spread: Boston -9
  • Nets vs. Celtics over/under: 224 points 
  • Nets vs. Celtics money line: Boston -420, Brooklyn +320
  • BKN: The Nets are 5-1 ATS in their last six games overall
  • BOS: The Celtics are 6-1 ATS in their last seven Wednesday games
  • Nets vs. Celtics picks: See picks at SportsLine

Why the Celtics can cover

Wing Jaylen Brown has developed into one of the most dynamic and explosive scorers in the game. Brown has the leaping ability to rise over any defender with ease, and he can also break down any defense at will. Brown averages 27 points and 7.2 rebounds per contest. In his last game, he racked up 37 points and nine boards.

Guard Derrick White is a well-rounded player and can score in different ways. White isn't afraid to penetrate the lane and finish at the basket as the Colorado product is a heads-up facilitator and constantly looks for his teammates. White averages 10.3 points, 3.1 rebounds, and 3.4 assists per game. On Jan. 24, he notched 23 points and six assists.

Why the Nets can cover

Guard Kyrie Irving is a great one-on-one player due to his outstanding ball control and court vision. Irving can dissect the defense in a hurry and can get a bucket in a variety of different ways. The Duke product averages 27.3 points, 5.1 rebounds, and 5.3 assists per contest. On Jan. 26, he dropped 40 points, five rebounds, and six assists. Irving has scored at least 30 points in six of his last seven games. 

Center Nicolas Claxton is an athletic, energetic, and active presence in the paint. Claxton has been a long and fluid defender in the lane with a knack for blocks. The Georgia product owns a soft touch in the lane and can throw it down with force. Claxton averages 13.1 points, 8.9 rebounds, and 2.7 blocks per game. He has logged a double-double in seven of his last nine contests.

How to make Celtics vs. Nets picks

SportsLine's model is leaning Over on the total, projecting 234 combined points. The model also says one side of the spread hits in nearly 60% of simulations. You can only see the model's pick at SportsLine.

So who wins Nets vs. Celtics? And which side of the spread hits in nearly 60% of simulations? Visit SportsLine now to see which side of the Celtics vs. Nets spread you need to jump on Wednesday, all from the model that has crushed its NBA picks, and find out.