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The Miami Marlins host a National League contest on Wednesday afternoon. Miami is 12-11 to begin the 2022 MLB season, though the Marlins are on a three-game losing streak. Miami aims to avoid a three-game sweep at the hands of the Arizona Diamondbacks. Arizona has won four of the last five games, improving to 12-13 overall. 

First pitch is at 12:40 p.m. ET in Miami. Caesars Sportsbook lists Miami as a -160 favorite on the money line, while the over-under, or total number of runs Vegas thinks will be scored, is 7.5 in the latest Diamondbacks vs. Marlins odds. Before you make any Marlins vs. Diamondbacks picks, you need to see the MLB predictions and betting advice from SportsLine's advanced computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times and it is off to a sizzling start to the 2022 season. It's on a 28-13 roll on top-rated MLB money-line picks through four weeks, returning over $1,100 for $100 players. Anyone following it has seen huge returns.

Now, the model has set its sights on Diamondbacks vs. Marlins, and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model's picks. Now, here are several MLB odds and betting lines for Diamondbacks vs. Marlins:

  • Diamondbacks vs. Marlins money line: Marlins -160, Dbacks +140 
  • Diamondbacks vs. Marlins over-under: 7.5 runs 
  • Diamondbacks vs. Marlins run line: Marlins -1.5 (+140)
  • ARZ: The Diamondbacks are 7-6 in road games 
  • MIA: The Marlins are 6-6 in home games
Featured Game | Miami Marlins vs. Arizona Diamondbacks

Why you should back the Diamondbacks

Arizona has notable edges against Miami. On offense, the Diamondbacks are No. 2 in the National League with 27 home runs this season, and also ranks near the top of the league with a sterling 10.1 percent walk rate. Marlins starting pitcher Elieser Hernandez has allowed six home runs in 2022, most in MLB, and he has a 5.75 ERA in four starts. 

On the mound, Arizona can lean on Madison Bumgarner. The 32-year-old veteran is a four-time All-Star and former World Series MVP, and Bumgarner is off to a tremendous start with a 1.17 ERA in five starts this season. Bumgarner has allowed only 1.13 base runners per inning this season, and left-handed hitters have a hideous .451 OPS against him in 2022. For his career, Bumgarner owns a 3.29 ERA with four times as many strikeouts as walks, and Miami is below-average in runs scored and strikeouts on offense this season.

Why you should back the Marlins

Miami should benefit from Arizona's issues on offense. The Diamondbacks enter with a bottom-three mark in the National League with only 83 runs scored. Arizona has the worst batting average (.188) in the NL this season, with the second-worst on-base percentage (.278) and the third-worst slugging percentage (.339) in the league. On the run prevention side, Arizona has one of the worst bullpens in the NL in 2022, allowing a 4.51 ERA that is the second-worst in the league, and Miami's starting pitching should be solid. 

Right-hander Elieser Hernandez averages 9.9 strikeouts and 2.2 walks per nine innings since the start of the 2020 season. In his career, Hernandez has held right-handed batters to a .290 on-base percentage, and Miami's bullpen has more than a strikeout per inning in 2022. The Marlins rank in the top four of the NL in bullpen ERA (3.06), and a close game favors Miami as a result.

How to make Diamondbacks vs. Marlins picks

SportsLine's model is leaning over on the run total, and it says one side of the money line has all the value. You can only get the model's MLB picks at SportsLine.

So who wins Diamondbacks vs. Marlins? And which side has all the value? Visit SportsLine now to see which side of Diamondbacks vs. Marlins you need to jump on Wednesday, all from the model that has crushed its MLB picks, and find out.