The New York Knicks welcome the Detroit Pistons to Madison Square Garden on Friday night. The Knicks are 0-1 this season after an overtime loss to the Memphis Grizzlies, and New York aims to improve on a 37-45 record from 2021-22. The Pistons began the season with a win over the Orlando Magic at home, and Detroit will now hit the road for the first time in 2022-23. Marvin Bagley III (knee), Alec Burks (foot), and Isaiah Livers (hip) are out for the Pistons, with Quentin Grimes (foot) out for the Knicks.

Caesars Sportsbook lists the Knicks as 7-point home favorites, and tip-off is scheduled for 7:30 p.m. ET. The total number of points Vegas thinks will be scored, or the over/under, is 219.5 in the latest Pistons vs. Knicks odds. Before you make any NBA predictions with the Knicks vs. Pistons match-up, you need to see the NBA predictions and betting advice from SportsLine's advanced computer model.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past four seasons. The model went a stunning 88-60 on all top-rated NBA picks last season, returning more than $2,100. Anyone following it has seen huge returns.

Now, the model has set its sights on Pistons vs. Knicks and just locked in its picks and NBA predictions. You can head to SportsLine now to see the model's picks. Now, here are several NBA odds and betting lines for Knicks vs. Pistons:

  • Knicks vs. Pistons spread: Knicks -7
  • Knicks vs. Pistons over/under: 219.5 points 
  • Knicks vs. Pistons money line: Knicks -285, Pistons +228
  • DET: The Pistons are 22-18-1 against the spread in the last 41 road games 
  • NYK: The Knicks are 16-24-1 against the spread in the last 41 home games 
  • Knicks vs. Pistons picks: See picks here
Featured Game | New York Knicks vs. Detroit Pistons

Why the Pistons can cover

Detroit started its season on a high note, outlasting the Orlando Magic in its season opener on Wednesday. The Pistons generated 31 assists in their first game, and five players scored at least 14 points. Detroit was above-average in free throw creation (22.0 attempts per game) and free throw accuracy (78.2%) last season, and the Pistons also secured 27.6% of available offensive rebounds in 2021-22.  

Cade Cunningham is a budding star for the Pistons. The former No. 1 overall pick averaged 21.0 points and 6.4 assists per game in his final 21 contests as a rookie last season, and he generated 18 points and 10 assists on Wednesday. On the other end, the Pistons have a penchant for havoc creation, forcing 14.6 turnovers per game and 7.7 steals per game last season. Detroit also blocked 4.8 shots per game in 2021-22, and ranked in the top eight of the NBA in 3-pointers allowed at 11.8 per game.

Why the Knicks can cover

New York fell just short of a win in its season opener, but the team performed well in a narrow, overtime loss to a contending team in Memphis. The Knicks had 18 offensive rebounds and 28 assists in the game, with six players in double figures from a scoring standpoint and a defense that held the Grizzlies below 40% shooting from the field. Last season, New York finished in the top six of the NBA in offensive rebound rate (29.1%) and free throw creation (24.1 attempts per game), with above-average marks in ball security (13.3 turnovers per game) and 3-point accuracy (35.7%).

On defense, New York is well-coached under Tom Thibodeau, and the Knicks held opponents to 1.1 points per possession in 2021-22. New York also finished in the top six of the league in 3-point percentage allowed (34.2%), field goal percentage (44.7%), and defensive rebound rate (74.0%).

How to make Knicks vs. Pistons picks

SportsLine's model is leaning Under on the total, with only one player projected to reach or exceed 20 points. The model also says one side of the spread hits in almost 70% of simulations. You can only see the model's NBA picks at SportsLine.

So who wins Knicks vs. Pistons? And which side of the spread hits in almost 70% of simulations? Visit SportsLine now to see which side of the Pistons vs. Knicks spread you need to jump on Friday, all from the model that has crushed its NBA picks, and find out.