The Cleveland Browns will seek a second straight division victory in NFL Week 2 when they visit the Pittsburgh Steelers as part of a Monday Night Football doubleheader. The Browns (1-0) dominated the AFC North-rival Cincinnati Bengals last Sunday, shutting down Joe Burrow and company in a 24-3 home victory. Now, they'll hit the road to face another rival. Pittsburgh (0-1) comes off a comprehensive 30-7 loss to the San Francisco 49ers at home in Week 1. Each team won their home matchup in this AFC North rivalry in 2022. The most recent meeting was a 28-14 Steelers victory in January, but Pittsburgh just missed the playoffs when the Dolphins beat the Jets. The Steelers finished 9-8 and in third place in the AFC North, while the Browns finished last at 7-10.

Monday's kickoff is set for 8:15 p.m. ET. Cleveland is a two-point favorite and the over/under for total points scored is 38 in the latest Browns vs. Steelers odds according to the SportsLine consensus. Before locking in any Steelers vs. Browns picks, make sure to check out the NFL predictions and betting advice from the SportsLine Projection Model.

The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 2 of the 2023 NFL season on an incredible 163-114 run on top-rated NFL picks that dates back to the 2017 season. It also is on a 17-7 roll on top-rated NFL picks since Week 7 of last season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has simulated Browns vs. Steelers 10,000 times and just revealed its coveted NFL picks and predictions. You can head to SportsLine now to see the model's picks. Here are several NFL odds and betting lines for Steelers vs. Browns:

  • Browns vs. Steelers spread: Cleveland -2
  • Browns vs. Steelers Over/Under: 38 points
  • Browns vs. Steelers money line: Cleveland -132, Pittsburgh +113
  • CLE: Browns are 2-8 against the spread in their last 10 games as road favorites
  • PIT: Steelers are 6-1 ATS in the last seven meetings with Cleveland
  • Browns vs. Steelers picks: See picks at SportsLine
  • Browns vs. Steelers live stream: fubo (try for free)

Why the Browns can cover

Cleveland's defense was dominant last week, and Pittsburgh had issues protecting Kenny Pickett against San Francisco. The quarterback was sacked five times and threw two interceptions. Now, he faces a Browns unit that pressured Burrow on 13 of 36 dropbacks and held him to 82 passing yards. Cleveland quarterback Deshaun Watson didn't have a strong day, throwing for 154 yards, one touchdown and one interception, but contributed to an elite run game.

The Browns, who are 8-8 against the spread in road games since 2021, rushed for 206 yards against Cincinnati. Nick Chubb rushed for 106 and should find room against a defense that allowed 152 to Christian McCaffrey last week. Chubb amassed 235 total yards over the two meetings with Pittsburgh last season. The Steelers front also will be without Cam Heyward, who had 10.5 sacks and made his sixth straight Pro Bowl in 2022 but had groin surgery this week. See who to back at SportsLine

Why the Steelers can cover

Pittsburgh is 5-0 straight-up and against the spread in its past five games at home. The Steelers also have been money in recent primetime games, covering the spread in four straight. T.J. Watt had three sacks against the 49ers and could help make the Browns one-dimensional. Browns quarterback Deshaun Watson completed 55% of his passes in Week 1 and was sacked three times and threw an interception. He was sacked seven times and threw two picks in the January meeting.

Cleveland's defense was stout in Week 1, but heavy rain also played a role. Kenny Pickett has flashed brilliance in his brief career and has players like George Pickens and Allen Robinson to throw to. They combined for 100 yards last week as Pickett threw for 232. The second-year quarterback threw two interceptions in the opener, but he had just one over his final eight starts last season. See who to back at SportsLine.

How to make Steelers vs. Browns picks

SportsLine's model is leaning Over the total, projecting 39 combined points. The model also says one side of the spread hits in well over 50% of simulations. You can only see the model's NFL picks and analysis at SportsLine

So who wins Steelers vs. Browns on Monday Night Football, and which side of the spread hits well over 50% of the time? Visit SportsLine now to see which side of the Steelers vs. Browns spread to back, all from the model that has returned more than $7,000 on top-rated NFL picks, and find out.