The Minnesota Golden Gophers and the Iowa Hawkeyes are set to square off in a Big Ten matchup at 3:30 p.m. ET on Saturday, Nov. 13 at Kinnick Stadium in Iowa City. The No. 20 Hawkeyes (7-2, 4-2 Big Ten), who were ranked second in the nation just a few weeks ago, lost two consecutive games prior to their win last weekend against Northwestern. The Gophers (6-3, 4-2) are coming off of their first loss in five games after a disappointing setback against Illinois on November 6.

The Hawkeyes are favored by 5.5 points in the latest Minnesota vs. Iowa odds from Caesars Sportsbook, and the over-under is set at 37. Before entering any Iowa vs. Minnesota picks, you'll want to see the college football predictions and betting advice from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,500 for $100 players on its top-rated college football picks against the spread. It also enters Week 11 of the 2021 season on a 31-20 run on all top-rated college football side picks. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Iowa vs. Minnesota and just locked in its coveted prediction and best bets. You can head to SportsLine now to see the model's picks. Here are several college football odds and betting lines for Iowa vs. Minnesota:

  • Iowa vs. Minnesota spread: Iowa -5.5
  • Iowa vs. Minnesota over-under: 37 points
  • Iowa vs. Minnesota money line: IOWA -220, MINN +180
Featured Game | Iowa Hawkeyes vs. Minnesota Golden Gophers

What you need to know about Iowa

After scoring just 14 points in two combined games against Purdue and Wisconsin in back-to-back losses, Iowa got back on track last week in a 17-12 win over Northwestern. Running back Tyler Goodson rushed for a touchdown and 141 yards on 21 carries. Alex Padilla was the team's primary quarterback after Spencer Petras was ineffective in Iowa's losses, but Padilla didn't exactly light up the Wildcats defense. He finished with 172 yards and completed 64 percent of his passes.

The Hawkeyes' success this season has been primarily due to its defense. Iowa has the seventh-best rush defense in the nation, and allows just 98 rushing yards per game. Iowa's pass defense has been strong as well, and has given up just 206 yards per game, but leads the country in interceptions with 19.

What you need to know about Minnesota

Minnesota came up short against Illinois on Saturday, losing 14-6. Gophers QB Tanner Morgan threw a touchdown, but he also tossed two interceptions on just 180 yards passing. Things don't figure to get much better this week against Iowa's top-rated defense, and Minnesota has one of the worst passing offenses in the nation. Morgan has thrown all but two of the team's passes this season and has completed less than 60 percent of them with just six touchdowns and seven picks.

Minnesota's rushing offense has been much more productive, led by Treyson Potts, who has 552 yards this season. Minnesota has two other backs that have averaged more than five yards per carry in Ky Thomas, who has 394 yards on the season, and Mar'Keise Irving, who has 381. Minnesota's pass defense has been tough as well, and has allowed fewer than 200 yards per game in 2021. Senior defensive lineman Boye Mafe leads the defense with six sacks in 2021.

How to make Minnesota vs. Iowa picks

The model has simulated Iowa vs. Minnesota 10,000 times and the results are in. We can tell you that the model is leaning over on the point total, and it's also generated a point-spread pick that is hitting in over 60 percent of simulations. You can only see the model's Iowa vs. Minnesota pick at SportsLine.

Who wins Iowa vs. Minnesota? And which side of the spread hits in over 60 percent of simulation? Visit SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks, and find out.