NL Central rivals square off on Thursday in the 2022 MLB Field of Dreams Game in Dyersville, Iowa, as the Chicago Cubs (45-65) and the Cincinnati Reds (44-66) clash. This contest is a tribute to the famous 1989 film "Field of Dreams" starring Kevin Costner. Both clubs have struggled this season, but should be playing with outstanding energy in this unique setting. Drew Smyly (4-6, 3.97 ERA) is on the hill for Chicago, while Nick Lodolo (3-3, 4.40 ERA) will get the start for Cincinnati.

First pitch is set for 7:15 p.m. ET. The latest 2022 Field of Dreams Game odds from Caesars Sportsbook lists Cincinnati as the slight -115 favorite (risk $115 to win $100). Chicago is listed at -105 and the over-under for total runs is set at nine in the Cubs vs. Reds odds. Before making any Reds vs. Cubs picks, you need to see the MLB predictions and betting advice from SportsLine's advanced computer simulation model.

The SportsLine Projection Model simulates every MLB game 10,000 times, and it is 299-254 on top-rated MLB money-line picks since the start of the 2021 season, returning over $800 for $100 players. This is the same model that pegged the 2021 Atlanta Braves at 10-1 as one of three best bets to win it all last season. Anybody who has followed it has seen profitable returns.

Now, the model has set its sights on Reds vs. Cubs and just locked in its picks and MLB predictions for the Field of Dreams Game 2022. You can head to SportsLine now to see the model's picks. Now, here are several MLB odds and betting lines for Cubs vs. Reds:

  • Cubs vs. Reds money line: Cincinnati -115, Chicago -105 
  • Cubs vs. Reds run line: Cincinnati -1.5 (+175) 
  • Cubs vs. Reds over-under: 9 runs
  • CIN: Reds are 5-2 in their last seven games versus left-handed starters
  • CHC: Under is 5-1 in Cubs' last six versus NL Central teams 
  • Cubs vs. Reds picks: See picks here.
Featured Game | Cincinnati Reds vs. Chicago Cubs

Why you should back the Cubs

Third baseman Patrick Wisdom is an important part of the Chicago lineup. Wisdom has showcased his strength to consistently smack the ball to all parts of the field. The 30-year-old is leading the team in both home runs (20) and RBIs (52). He's also a reliable defender in the corner.

Shortstop Nico Hoerner is a natural hitter due to his elite bat speed and awareness of the strike zone. Hoerner has shown his capability of hitting for a good average and consistently getting on base. The 25-year-old also owns a solid throwing arm with a smooth glove. He's 17th in the league in batting average (.300) along with 37 RBIs.

Why you should back the Reds

First baseman Joey Votto is a stellar hitter with superb awareness and bat control. Votto owns a steady eye at the plate and power to all parts of the field. The six-time All-Star has always been a strong run-producer and will be mic'd up in this contest. Votto has belted 11 home runs with 41 RBIs. In his last contest, he went 2-for-3 with a double and one run was driven in.

Shortstop Kyle Farmer maintains a strong throwing arm and reliable glove in the infield. Farmer has steady footwork, hands, and reaction time. The 31-year-old is able to consistently make contact and get on base. His batting average is currently .255 with six home runs and 51 RBIs. He's logged two-plus hits in back-to-back games.

How to make Cubs vs. Reds picks for Field of Dreams

SportsLine's model is leaning over on the run total, projecting 9.4 combined runs. It also says one side of the money line has all the value. You can only see the model's MLB picks at SportsLine.

So who wins Reds vs. Cubs? And which side has all the value for the 2022 MLB Field of Dreams Game? Visit SportsLine now to find out which side of Reds vs. Cubs you need to jump on, all from the model that has crushed its MLB picks, and find out.