The Cincinnati Reds (34-57) and the St. Louis Cardinals (50-44) face off in the first contest of their three-game series on Friday. The Cardinals currently sit in second place in the NL Central standings. Meanwhile, the Reds have struggled thus far and have the second-worst record in the MLBAdam Wainwright (6-7, 3.00 ERA) is on the hill for St. Louis, while Graham Ashcraft (4-2, 4.45 ERA) gets the nod for Cincinnati. 

First pitch is set for 6:40 p.m. ET. St. Louis is the -145 money line favorite (risk $145 to win $100) in the latest Cardinals vs. Reds odds from Caesars Sportsbook, while Cincinnati is a +122 underdog. The over-under for total runs scored is 10. Before making any Reds vs. Cardinals picks, be sure to check out the latest MLB predictions and betting advice from the SportsLine Projection Model.

The SportsLine Projection Model simulates every MLB game 10,000 times, and it is 280-240 on top-rated MLB money-line picks since the start of the 2021 season, returning over $500 for $100 players. This is the same model that pegged the 2021 Atlanta Braves at 10-1 as one of three best bets to win it all last season. Anybody who has followed it has seen profitable returns.

Now, the model has set its sights on Cardinals vs. Reds, and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model's picks. Here are several MLB odds and betting lines for Reds vs. Cardinals:

  • Cardinals vs. Reds money line: St. Louis -145, Cincinnati +122
  • Cardinals vs. Reds run-line: Cincinnati +1.5 (-130)
  • Cardinals vs. Reds over-under: 10 runs
  • STL: The Cardinals are 5-2 in their last seven overall
  • CIN: The Reds are 4-0 in their last four home games
  • Cardinals vs. Reds picks: See picks at SportsLine
Featured Game | Cincinnati Reds vs. St. Louis Cardinals

Why you should back the Cardinals

Second baseman Tommy Edman is an impact player for the Cardinals. Edman is patient at the plate with a compact, line-drive swing. The ball will explode off his bat and find its way all across the diamond. The 27-year-old is also extremely quick and has become a stolen base threat. He's tied for fourth in the MLB in stolen bases (20). Edman is hitting .259 with seven home runs and 33 RBIs. 

Outfielder Dylan Carlson is a versatile defender with a well-rounded skillset. Carlson has great awareness of the strike zone with pinpoint throwing accuracy from the outfield. The 23-year-old owns a batting average of .257 along with five home runs and 26 RBIs. On July 14, he went 2-for-3 with a double. 

Why you should back the Reds

Third baseman Brandon Drury is a smooth hitter with a compact swing. Drury's swing is effortless with the strength to smash the ball to different gaps on the diamond. The 29-year-old is also a reliable defender with a strong throwing arm. He's leading the team in batting average (.278), home runs (18), RBIs (52), and OBP (.336). 

Shortstop Kyle Farmer has excellent footwork on the infield. Farmer plays solid defense with quick reads and instincts. The 31-year-old also has a strong throwing arm with good velocity. He can produce offensive sparks when needed and owns a batting average of .260 along with 46 RBIs. Farmer has logged six RBIs over his past five games.

How to make Reds vs. Cardinals picks

SportsLine's model is leaning under on the total, projecting 9.5 combined runs. It also says one side of the money line has all the value. You can only get the model's MLB picks at SportsLine.

So who wins Cardinals vs. Reds? And which side has all the value? Visit SportsLine now to see which side you need to jump on, all from the model that has crushed its MLB picks, and find out.