The Los Angeles Dodgers (48-28) host the San Diego Padres (46-33) in a divisional matchup on Saturday evening. The Dodgers head into this contest on a three-game winning streak. Meanwhile, San Diego has lost five of its last six games. Los Angeles currently sits in first place in the division standings and San Diego is in second. Yu Darvish (7-3, 3.26 ERA) will be starting for San Diego. Tyler Anderson (8-1, 3.23 ERA) is on the mound for Los Angeles.

First pitch is set for 7:15 p.m. ET. Caesars Sportsbook lists Los Angeles as the -145 money-line favorite (risk $145 to win $100) in the latest Padres vs. Dodgers odds, while San Diego is a +122 underdog. The over-under for total runs scored is eight. Before making any Dodgers vs. Padres picks, be sure to check out the latest MLB predictions and betting advice from the SportsLine Projection Model.

The SportsLine Projection Model simulates every MLB game 10,000 times and it is off to a strong start to the 2022 season. It's on a 59-51 run on top-rated MLB money-line picks through 12 weeks. This is the same model that pegged the 2021 Atlanta Braves as one of three best bets to win it all last season at +1000. Anybody who has followed it has seen profitable returns.

Now, the model has set its sights on Dodgers vs. Padres, and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model's picks. Here are several MLB odds and betting lines for Padres vs. Dodgers:

  • Dodgers vs. Padres money line: Los Angeles -145, San Diego +122
  • Dodgers vs. Padres run line: Los Angeles -1.5 (+140)
  • Dodgers vs. Padres over-under: 8 runs
  • SD: Padres are 10-2 in their last 12 road games vs. a left-handed starter
  • LAD: Under is 5-0 in Dodgers' last five games following a win
  • Dodgers vs. Padres picks: See picks at SportsLine
Featured Game | Los Angeles Dodgers vs. San Diego Padres

Why you should back the Dodgers

First baseman Freddie Freeman is having a terrific first season in Los Angeles. Freeman has the bat control and bat speed to spray the ball all over the diamond. The five-time All-Star owns an impressive frame and solid plate discipline. Freeman has a batting average of .303 along with nine dingers and 48 RBIs.

Center fielder Cody Bellinger possesses exceptional hitting skills and plate awareness. Bellinger has displayed home-run power and run-producing qualities. The two-time All-Star also offers position flexibility on the defensive side. Bellinger currently has 11 home runs and 31 RBIs. In his last contest, he went 1-for-3 with a two-run bomb. 

Why you should back the Padres

Third baseman Manny Machado has an absolute cannon for an arm and is very rangy on the defensive end. Machado owns outstanding bat control with power to all parts of the field. The five-time All-Star is fourth in the majors in batting average (.326) while leading the team in home runs (12), RBIs (46), and hits (84). Machado recently returned from an ankle injury and looks to get back on track.

Left fielder Jurickson Profar is a phenomenal athlete who owns a combination of speed, power, and plate discipline. Profar owns solid instincts at the plate and on the defensive end. The 29-year-old is hitting .250 with eight home runs and 38 RBIs. In his last outing, he went 2-for-4 with two doubles. 

How to make Padres vs. Dodgers picks

SportsLine's model is leaning over on the total, projecting 8.4 combined runs. It also says one side of the money line has all the value. You can only get the model's MLB picks at SportsLine.

So who wins Dodgers vs. Padres? And which side has all the value? Visit SportsLine now to see which side you need to jump on, all from the model that has crushed its MLB picks, and find out.