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The St. Louis Cardinals (15-25) and the Boston Red Sox (22-18) clash in a battle on Sunday Night Baseball. The Cardinals are currently on a two-game win streak, while Boston has lost two in a row and four of its last five outings. On Saturday, the Cardinals topped the Red Sox 4-3. Boston is 5-2 in its last seven during Game 3 of a series, while the Cardinals are 4-0 in their last four versus the American League East.

The first pitch is set for 7:10 p.m. ET from Fenway Park. St. Louis is listed at -115 in the money line (risk $115 to win $100) in the latest Cardinals vs. Red Sox odds from Caesars Sportsbook. The over-under for total runs scored is 10. Before making any Red Sox vs. Cardinals picks, be sure to see the MLB predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times. It went 331-285 on top-rated MLB money line picks (+357) over the past two seasons, It has opened the 2023 MLB season on a 17-12 roll on all-top rated MLB picks. Anybody who has followed it has seen profitable returns.

Now, the model has dialed in on Cardinals vs. Red Sox and revealed its predictions and best bets. You can visit SportsLine now to see the model's MLB picks. Here are the MLB odds and betting trends for Red Sox vs. Cardinals:

  • Cardinals vs. Red Sox moneyline: St. Louis -115, Boston -105
  • Cardinals vs. Red Sox run-line: Boston +1.5 (-145)
  • Cardinals vs. Red Sox over-under: 10 runs
  • STL: Cardinals are 5-1 in their last 6 overall
  • BOS: Red Sox are 6-2 in their last 8 home games
  • Cardinals vs. Red Sox picks: See picks at SportsLine
Featured Game | Boston Red Sox vs. St. Louis Cardinals

Why you should back the Red Sox

Right fielder Alex Verdugo is a versatile player with solid awareness at the plate and great pitch recognition skills. The 26-year-old is batting .299 with five home runs and 18 RBI. He's tallied a hit in six of his last 10 games, including on May 9 against the Atlanta Braves when he went 3-for-5 with a double and one run scored.

Left fielder Masataka Yoshida is having a great start to his rookie campaign. Yoshida owns elite plate discipline and constantly makes contact when at bat. A two-time batting champion in Japan, Yoshida is leading the team in batting average (.307) and OBP (.390) with 24 RBI. On Friday, he went 2-for-3 with one double and one run scored. See which team to back here

Why you should back the Cardinals

First baseman Paul Goldschmidt is a big-time slugger who has excellent pitch recognition skills and drives the ball into any spot on the diamond. The seven-time All-Star is eighth in the NL in batting average (.310) with seven home runs and 20 RBI. In Friday's game against the Red Sox, Goldschmidt was 3-for-5, collecting his third three-hit game over his last seven starts.

Third baseman Nolan Arenado is another playmaker who has natural power and run-producing abilities. The 32-year-old is a 10-time Gold Glove winner and owns an elite arm. Arenado is batting .252 with five home runs and 22 RBI. On May 12, he went 4-of-5 with a two-run homer. See which team to back here

How to make Cardinals vs. Red Sox picks

SportsLine's model is leaning Under on the total, projecting 9.6 combined runs. It also says one side of the money line has all of the value. You can only get the model's MLB picks at SportsLine.

So who wins Red Sox vs. Cardinals? And which side of the money line has all the value? Visit SportsLine now to see which side of the money line to jump on, all from the advanced model that's on a 17-12 roll, and find out.