Two teams in the NFL playoff picture wrap up the Week 15 NFL schedule when the New Orleans Saints (10-3) host the Indianapolis Colts (6-7) at 8:15 p.m. ET on Monday Night Football. The Colts desperately need a win to stay alive in the AFC playoff race, while the Saints are hoping to earn a bye in the NFC playoff bracket. DraftKings is hosting a $1.11M Monday Night Showdown, while FanDuel has a $650K Monday Night Special, and daily Fantasy football players will be searching the NFL DFS player pool for value from players like Drew Brees, Michael Thomas, Alvin Kamara, Jacoby Brissett and Marlon Mack. Before setting any Monday Night Football DFS lineups for Saints vs. Colts, be sure to see the NFL DFS advice from SportsLine's Mike McClure. He's won almost $2 million as a daily Fantasy pro, and his top NFL DFS picks, stacks, optimal lineups and strategy can help you separate from the pack in this showdown slate.

He's crushed his NFL DFS picks in 2019, including a strong 3x return on DraftKings in the Week 3 main slate. On Sunday of Week 5, his optimal lineup finished in the top 1 percent of tournaments on DraftKings, with his four core players -- Deshaun WatsonMichael ThomasChristian McCaffrey and Will Fuller -- combining for a whopping 196.34 points, enough to cash in tournaments by themselves. He followed that up by cashing his FanDuel and DraftKings lineups on Sunday Night Football and Monday Night Football in Week 6 and then cashed everywhere on his SNF lineups yet again in Week 7.

He continued his roll with wins on both sites on the main slate, SNF and MNF in Week 8. He added 5x returns on his optimal lineups on both sites in Week 9 and cashed in main slate tournaments on both sites in Week 11. His Week 13 main slate lineups returned at least 10x on DraftKings and produced returns as high as 40x in higher-stakes tournaments. And last week, all of his lineups cashed handily. Anybody who has been following him has seen huge returns. 

Now, he has turned his attention to the Saints vs. Colts DFS player pool and locked in his top daily Fantasy football picks. You can only see them by heading to SportsLine.

We can tell you one of McClure's top NFL DFS picks for Colts vs. Saints is Brissett. Despite a growing injury list around him, Brissett has still returned consistent value for daily Fantasy players, including at least 3x on DraftKings his last two games. He's thrown for 570 yards and three touchdowns during that span. He's also found the end zone twice on the ground twice in the past four weeks.

Brissett is in position to roll against a New Orleans defense that ranks 20th in the NFL against the pass (244.1 yards per game). The Saints have surrendered at least 300 passing yards to three of the last four quarterbacks they've faced (Matt Ryan, Jameis Winston, Jimmy Garoppolo), including an eye-popping 349-4 passing line for Garoppolo in Week 14. And with the Colts (+9) listed as heavy underdogs, game flow could set up well for Brissett to throw early and often, increasing his chances of returning value.

Part of McClure's optimal NFL DFS strategy for Monday Night Football also includes rostering Thomas. Already leading the NFL in receptions (121) and receiving yards (1,424), Thomas is positioned to go off for massive numbers yet again on Monday Night Football against a banged-up Indianapolis secondary. The Colts are already below average (21st) in passing defense and could be without starting safety Malik Hooker (foot) and corner Pierre Desir (groin), who are both questionable. 

McClure is also targeting a player who could go off for massive numbers on Monday Night Football because of a dream matchup. This pick could be the difference between winning your tournaments and cash games or going home with nothing.

So who is DFS pro Mike McClure putting in his optimal NFL DFS lineup on Monday Night Football? Visit SportsLine now to see the full optimal tournament lineups for Saints vs. Colts from a professional DFS player who has almost $2 million in career winnings, and find out.