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An NFC North battle is on tap between the Detroit Lions and the Green Bay Packers at 1 p.m. ET on Sunday at Lambeau Field. The Packers beat Minnesota 43-34 in their season opener. The Lions collapsed and lost to Chicago, 27-23. Green Bay is favored by six points in the latest Packers vs. Lions odds from William Hill, and the over-under is set at 49.5. Before entering any Lions vs. Packers picks, you'll want to see the NFL predictions from the model at SportsLine.

The model, which simulates every NFL game 10,000 times, is up over $7,400 for $100 players on its top-rated NFL picks since its inception five years ago. It went a perfect 4-0 on top-rated NFL picks in Week 1, including calling easy covers by the Ravens and Bills. The model enters Week 2 on an incredible 100-65 roll on top-rated NFL picks that dates back to the 2017 season. 

The model ranked in the Top 10 on NFLPickWatch in three of the past four years on straight-up NFL picks and beat more than 95 percent of CBS Sports office pool players three times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Packers vs. Lions. You can head to SportsLine to see its picks. Here are several NFL betting lines for Lions vs. Packers:

  • Packers vs. Lions spread: Packers -6
  • Packers vs. Lions over-under: 50 points
  • Packers vs. Lions money line: Green Bay -265, Detroit +225

Why the Packers can cover

The Packers came out on top against the Minnesota Vikings by a score of 43-34 on Sunday. Aaron Rodgers passed for four TDs and 364 yards on 44 attempts with a passer rating of 127.5. Rodgers has two-plus TD passes in four of his past five home starts vs. the Lions. 

Davante Adams had career-high 14 receptions for 156 yards and two TDs in Week 1, He has six TD catches in his past six games vs. Detroit. Aaron Jones is aiming for his fifth consecutive home game with a TD. Matt LaFleur won both of his matchups vs. Detroit last year in his first season as Green Bay's head coach.     

What you need to know about the Lions

Detroit squandered a 17-point third-quarter lead in its 27-23 season-opening loss to Chicago. Adrian Peterson was a bright light for Detroit, as the future Hall of Famer picked up 93 yards on the ground on 14 carries in his Lions debut. He is gunning for his ninth game in row at Green Bay with a rushing TD.

Matthew Stafford has a 100-plus passer rating in four of his past five starts vs. Green Bay. Marvin Jones has seven career TD catches in seven career games vs. Green Bay. Kenny Golladay missed the game against the Bears because of a hamstring injury and he has already been ruled out for this matchup. He led the NFL with 11 TD catches in 2019. 

How to make Packers vs. Lions picks

SportsLine's model has simulated Packers vs. Lions 10,000 times and the results are in. The model is leaning over on the total, and it's also generated a point-spread pick that is hitting in over 50 percent of simulations. You can only see the pick at SportsLine.

So who wins Packers vs. Lions? And which side of the spread hits in over 50 percent of simulations? Visit SportsLine now to see which side of the Lions vs. Packers spread to jump on Sunday, all from the model that enters Week 2 of the NFL season on an incredible 100-65 roll.