Uruguay is gaining momentum and will try to maintain it when it faces Colombia on Saturday in the quarterfinals of the 2021 Copa America in Goiania, Brazil. Uruguay won its last two games to finish second in Group A behind Argentina, while Colombia lost its last two to finish third in 2021 Copa America's Group B. Uruguay is the ninth-ranked team in the world and holds a 20-9-13 edge in the all-time series with Colombia, which ranks 15th. La Celeste has won the tournament a record 15 times, most recently in 2011, while Colombia won its only Copa America in 2001.

Kickoff from Olimpico Stadium is set for 6 p.m ET. Uruguay is the +125 favorite (risk $100 to win $125) on the 90-minute money line in William Hill Sportsbook's latest Uruguay vs. Colombia odds, with Colombia listed as the the +270 underdog. The over-under for total goals scored is set at 1.5. Before betting the Colombia vs. Uruguay match or making any 2021 Copa America predictions, you have to see what soccer insider Martin Green is saying

After working in the sports betting industry for several years, Green became a professional sports writer and handicapper and has covered the game worldwide. Since then, his expert soccer picks have been spot-on. Green has generated nearly  $19,000 for $100 bettors since the 2017-18 season. He has his finger on the pulse of the game all over the globe.

Now, Green has taken an in-depth look at Uruguay vs. Colombia. You can head to SportsLine to now see his Copa America 2021 picks. Here are the betting lines and trends for Colombia vs. Uruguay:  

  • Uruguay vs. Colombia spread: Uruguay -0.5 (+130)
  • Uruguay vs. Colombia over-under: 1.5 goals (over -170, under +140)
  • Uruguay vs. Colombia money line: Uruguay +125, Colombia +270, Draw +200 
  • URU: Luis Suarez is Uruguay's top scorer all-time with 64 goals in 122 matches 
  • COL: Luis Muriel has 40 goals over his two seasons with Atalanta in Serie A

Why you should back Uruguay

La Celeste is 8-2-2 in its last 12 matches against Colombia and boasts two of the world's top strikers in Luis Suarez and Edinson Cavani. Both are 34 years old but remain dangerous finishers. Each had a goal in the last meeting between the teams, a 3-0 Uruguay victory in a 2022 World Cup qualifying match in November. Suarez led Atletico Madrid to Spain's La Liga championship with 21 goals in his first season there after scoring 146 in six years at Barcelona. Cavani had 10 goals while starting just 13 times in 26 appearances with Manchester United.

Uruguay is 4-2-2 in its past eight games, with the only losses to South American powers Argentina and Brazil. Colombia, meanwhile, has won just twice in its past eight (2-2-4). It scored just three goals in the four group-stage matches, while Uruguay allowed two and has posted five clean sheets over the past eight matches. Veteran Diego Godin teams with Atletico Madrid's Jose Gimenez to form a strong barrier in front of goalkeeper Fernando Muslera. Federico Valverde and Rodrigo Bentancur also have been impressive and give Uruguay the edge in the midfield battle.   

Why you should back Colombia

The Colombians have struggled so far as manager Reinaldo Rueda tries to find the right mix from his talented attackers. Duvan Zapata and Luis Muriel excelled together with Atalanta in Italy's Serie A last season, combining for 37 goals and 17 assists. They could be paired together Saturday for the first time in the tournament. Rueda has another talented option in 25-year-old Rafael Borre, who was the top scorer in Argentina's top flight with 12 goals in 20 matches for River Plate. 

The threat so far has come from Edwin Cardona and Luis Diaz, the only players to score during the run of play. Both will need to step up to fill the void left by Cuadrado's yellow-card suspension. Miguel Borja, who has 14 goals in 23 matches in two seasons at Colombia's Atletico Junior, scored on a penalty kick for the team's other goal. Experienced goalkeeper David Ospina yielded just four goals in group play.

How to make Uruguay vs. Colombia 2021 Copa America picks

Green has taken a look at the Uruguay vs. Colombia matchup from all angles and is leaning over on the goal total. He also has revealed his in-depth Copa America 2021 analysis and three best bets, including two with plus-money payouts. He's only sharing his expert picks at SportsLine.

So who wins Colombia vs. Uruguay? And where does all the betting value lie? Visit SportsLine now to see the best bets for Uruguay vs. Colombia, all from the soccer expert who has his finger on the pulse of the game all over the world, and find out.