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One of the marquee matchups on the Week 10 college football schedule features Jayden Daniels and the No. 13 LSU Tigers traveling to play the No. 8 Alabama Crimson Tide in Tuscaloosa. Daniels has accounted for 30 total touchdowns this season, helping the Tigers average 47.4 points per game, the most in the nation. Meanwhile, the Crimson Tide have given up 21 points or less in each of their last six games. The latest Week 10 college football odds from the SportsLine consensus list Alabama as 3-point favorites at home for that 7:45 p.m. ET matchup on CBS.

Elsewhere in college football, Washington is a 3-point favorite against USC and Oklahoma is a 6-point favorite at Oklahoma State in the final scheduled Bedlam Series matchup. Before locking in any Week 10 college football picks on those games or others, be sure to see the latest college football predictions from SportsLine's proven model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, it has generated a stunning profit of well over $2,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has turned its attention to the latest college football odds for Week 10 and locked in picks for every FBS matchup. Head here to see every pick.

Top college football predictions for Week 10

One of the college football picks the model is recommending for Saturday: No. 18 Utah (-11) bounces back against Arizona State at 2 p.m. ET on Saturday afternoon. The Utes suffered their second loss of the season against No. 8 Oregon last week in a blowout while Arizona State is coming off its first Pac-12 win under head coach Kenny Dillingham over Washington State.

However, the model is predicting some market overreaction on both sides. Utah has won five of the last seven in this rivalry, including wins in each of the last three head-to-head meetings. The Utes won 21-3 in 2019, 35-21 in 2021 and 34-13 last season on the road, covering the spread in all three matchups. Despite giving up 35 points at home to Oregon last week, Utah has one of the nation's best defenses. The Utes rank 18th in the country in points allowed per game (17.5) while the Arizona State offense ranks 118th in scoring (19.6 ppg). That's a big reason why the model has Utah covering in well over 60% of simulations.

Another prediction: No. 2 Georgia (-15) cruises to another blowout win at home against Missouri in a SEC on CBS matchup that kicks off at 3:30 p.m. ET. The Bulldogs are coming off their best stretch of the season, winning their last three games by 78 combined points. Georgia also put on show in its last home game at Sanford Stadium, posting a dominant 51-13 victory over Kentucky.

Quarterback Carson Beck threw for 389 yards and four touchdowns in the win over the Wildcats. The junior signal-caller has thrown for more than 300 yards in four of his last five games, racking up 11 touchdown passes during that span. In addition, the Bulldogs have won 20 consecutive games at home and they've won 15 straight against an opponent from the SEC. The model projects Beck will throw for more than 245 yards and two touchdowns on Saturday as the Bulldogs cover the spread in over 70% of simulations. See which other teams the model likes here.

How to make college football picks for Week 10

The model has also made the call on who wins and covers in every other FBS matchup in Week 10, and it's calling for several underdogs to win outright. You can only get every pick for every game at SportsLine.

So what college football picks can you make with confidence, and which underdogs win outright? Check out the latest college football odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned well over $2,000 in profit since its inception, and find out.

College football odds for top Week 10 games 

See full Week 10 college football picks, odds, predictions here.

Saturday, Nov. 4

UConn vs. Tennessee (-35, 55.5)

Notre Dame vs. Clemson (+3, 44.5)

Arkansas vs. Florida (-3, 49)

Ohio State vs. Rutgers (+19, 42)

Texas A&M vs. Ole Miss (-3, 52)

Kansas State vs. Texas (-3.5, 50)

Arizona State vs. Utah (-11, 39)

Army vs. Air Force (-17.5, 32)

Missouri vs. Georgia (-15, 55.5)

Virginia Tech vs. Louisville (-10, 48.5)

Penn State vs. Maryland (+8.5, 50.5)

Florida State vs. Pittsburgh (+21.5, 50.5)

Oklahoma vs. Oklahoma State (+6, 62)

California vs. Oregon (-24.5, 59.5)

Purdue vs. Michigan (-33, 53)

Washington vs. USC (+3, 77.5)

LSU vs. Alabama (-3, 61.5)

Oregon State vs. Colorado (+13, 61)

UCLA vs. Arizona (+2.5, 50)