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Two of the NL's best teams collide when the Milwaukee Brewers and San Diego Padres face off on Tuesday at Petco Park in San Diego. The Padres (28-14) are just a half-game behind the Dodgers (28-13) for the best record in the league. Meanwhile, the Brewers (26-16) lead the NL Central and have the fourth-best record in the NL. On Tuesday two Cy Young Award winners -- Milwaukee's Corbin Burnes and San Diego's Blake Snell -- square off. Milwaukee is a -135 money-line favorite in the latest Brewers vs. Padres odds from Caesars Sportsbook, while San Diego is a +115 underdog.

First pitch is set for 9:40 p.m. ET. The game is one of 15 on the MLB schedule on Tuesday. Elsewhere in the majors, the Yankees try to bounce back from their first three-game losing streak of the season, and the Twins look to run their winning streak to six. Before making any MLB picks or parlays, be sure to check out the MLB predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times and it is off to a strong start to the 2022 season. It's on a 41-30 roll on top-rated MLB money-line picks through seven weeks, returning almost $600 for $100 players. Anyone following it has seen huge returns.

Now, the model has locked in four confident MLB best bets for Tuesday. All the games occur at 7:20 p.m. ET or later, so there's still plenty of time to make these MLB picks. If you successfully parlay the picks, you'd be looking at a payout of almost 32-1. You can only see the model's MLB picks at SportsLine.

Top MLB picks today

The model, which ran 10,000 simulations on all 15 of Tuesday's games, is taking Boston (+135) to beat the White Sox at 8:10 p.m. ET (see tickets at StubHub). The Red Sox are surging, having won five straight games, which is tied for the longest active streak in the majors. In those five games, Boston's lineup has been hot, averaging 7.6 runs per game.

Rafael Devers has been key to the team's success. The Red Sox third baseman ranks seventh in the majors in batting average (.335), ninth in OPS (.959) and 14th in home runs (nine). Earlier this season, Devers went 2-for-2 with a double, a walk and an RBI against Dylan Cease, who is set to start for Chicago on Tuesday.

Featured Game | Chicago White Sox vs. Boston Red Sox

How to make MLB picks and parlays for Tuesday

The model also locked in three other best bets for Tuesday, including a must-see play on an even bigger underdog. You can see the model's MLB best bets and parlay only at SportsLine.

What MLB picks should you target for a payout of almost 32-1? And what underdog does the model like on Tuesday? Visit SportsLine now to see the MLB best bets from an advanced model that is on a 41-30 roll on top-rated MLB money-line picks through seven weeks.