The top of the passing touchdown leaderboard looks as expected, with Lamar Jackson, Patrick Mahomes, Josh Allen and Justin Herbert among the top five. But an unexpected name also appears at the very top, Jared Goff. The former No. 1 overall pick has also been one of the top Fantasy football picks this year as the catalyst of a high-flying Lions offense. With a matchup versus the Patriots on Sunday, where does Goff fall in the Week 5 Fantasy football rankings for quarterbacks? Jackson went off versus New England in Week 3, but the Pats contained Aaron Rodgers last week. Should you roster Goff in your Week 5 Fantasy football lineups despite his history versus New England, and what other Fantasy football start-sit decisions should you contemplate? Before setting your Fantasy football lineups, be sure to check out the Week 5 Fantasy football rankings from the advanced computer model at SportsLine.

When it comes to ranking players, SportsLine's model beat human experts in Fantasy football for the past several seasons especially when there were big differences in ranking. Over the course of a season, that could literally be the difference between winning your league or going home empty-handed.

Last week, the model was extremely high on Lions running back Jamaal Williams, saying he'd finish as a top-10 player at his position. The result: Williams recorded 19 carries for 108 yards and two touchdowns in Detroit's loss against the Seahawks. Anybody who had him in their lineup was well on their way to a huge week.

Now, the model, which simulates every NFL game 10,000 times, has revealed its Fantasy football rankings for Week 5 of the 2022 NFL season. Head to SportsLine now to see them.

Top Week 5 Fantasy football picks 

One player the model is high on this week: Vikings wide receiver Adam Thielen. The veteran has increased his production in every game, going from 36 yards in Week 1 to 72 receiving yards last week. A divisional matchup with Chicago awaits in Week 5, and Thielen has lived in the end zone in recent matchups with the Bears.

Thielen didn't play in either game versus Chicago last year, but in 2020, he caught three touchdown passes across the two games. Chicago has only played one offense that ranks among the top half of the league in passing yards, which was Green Bay in Week 2, and Allen Lazard found the end zone in that contest, while Sammy Watkins had 93 yards. The model pegs Thielen as a top-20 WR for this week, making him a solid WR2 in the Week 5 Fantasy football WR rankings. See who else to target here.

And a massive shocker: Steelers running back Najee Harris, who's scored a touchdown in each of Pittsburgh's road games this season, stumbles big-time and doesn't even crack the top 20 at his position. Harris recorded 18 carries for 74 yards in Pittsburgh's loss against the Jets last Sunday. Pittsburgh's offense struggled to find a rhythm against the Jets and the Steelers are expected to start rookie QB Kenny Pickett moving forward.  

That doesn't bode well for Harris' Fantasy value with teams expected to stack the box against an inexperienced signal-caller. Plus, Harris and the Steelers will square off against the Buffalo Bills, who are giving up just 234.5 yards per game this season, which ranks first in the NFL. With such a tough matchup on Sunday, Harris is a player to consider putting on the bench in Week 5. See who else to fade here.

How to set Week 5 Fantasy football rankings

The model is also calling for a surprising quarterback you aren't even thinking about to finish in the top 10 of its Week 5 Fantasy football rankings. This pick could be the difference between winning big and going home with nothing. You can only see who it is here.

So who should you start and sit this week? And which surprising quarterback could lead you to victory? Visit SportsLine now to get Week 5 Fantasy football rankings for every position, plus see which QB is going to come out of nowhere to crack the top 10, all from the model that has outperformed experts big-time.