Valdes-Scantling had four receptions on 10 targets for 123 yards and a touchdown in Sunday's 34-31 loss to the Vikings.
Valdes-Scantling moved into the starting lineup with Allen Lazard (shoulder) missing the contest. The 27-year-old took full advantage of the opportunity, breaking off a 75-yard touchdown while nearly matching his total season output in just one game. Lazard's status for Week 12 is still up in the air, so Valdes-Scantling could get another start alongside Davante Adams against the Rams. That scenario could result in another high-usage game for MVS if the latter has to deal with Jalen Ramsey.