Oregon State was one of the most unlikely Sweet 16 teams in last year's NCAA Tournament as a 12-seed that eventually made it to the Elite 8. To get there, the Beavers won their Sweet 16 matchup against Loyola-Chicago on the strength of a 22-point performance from Ethan Thompson. There are no 12-seeds in the Sweet 16 of the 2022 March Madness bracket, but No. 15 Saint Peter's and No. 11 Michigan could make waves. The 2022 NCAA Tournament bracket resumes Thursday with the March Madness Sweet 16.

The Wolverines have overcome a plethora of adversity this season to get hot at the right time, while the Peacocks have become the darlings of the 2022 NCAA bracket. Can you count on either to continue their run through the NCAA Tournament 2022 and on to the Elite 8? Before locking in your March Madness predictions, be sure to check out the 2022 NCAA bracket picks from the advanced computer model at SportsLine.

SportsLine's advanced computer model absolutely crushed its March Madness picks last tournament, beating over 92 percent of all CBS Sports brackets for the second time in three years. The model also nailed a whopping three teams in the Final Four last year. 

It knows how to spot an upset as well. The same model has produced brackets that have nailed 17 first-round upsets by double-digit seeds. It also nailed some massive upsets last tournament, including predicting the championship game between Gonzaga and Baylor, and hit Houston's Midwest Region win even though the Cougars weren't the No. 1 seed.

There's simply no reason to rely on luck when there's proven technology to help you dominate your 2022 March Madness picks. Now, the model has simulated every possible matchup for the remainder of the 2022 NCAA Tournament and revealed its updated bracket. You can only see it over at SportsLine.

Top 2022 NCAA Tournament Sweet 16 picks

One team to back in 2022 March Madness brackets: No. 3 Purdue over No. 15 seed Saint Peter's. Saint Peter's has had a few days to cool off after knocking off Kentucky and Murray State in the opening rounds of the NCAA Tournament 2022.

Purdue appears to be firing on all cylinders after beating Texas and Yale by double-digits. Center Zach Edey is coming off a strong showing in the victory over the Longhorns, recording a double-double with 11 points and 10 rebounds. The 7-foot-4 sophomore has now recorded 11 double-doubles this season and is expected to be heavily involved in Purdue's game plan against the Peacocks. Saint Peter's doesn't play with a traditional center and no starter stands over 6-foot-7. That's a major reason why SportsLine's model has Purdue ending Saint Peter's Cinderella run in the 2022 NCAA bracket.

Another team to back in your 2022 NCAA Tournament picks: No. 4 seed UCLA cruises to the Elite Eight with a win over No. 8 seed North Carolina in the East Region. UCLA was a surprise Final Four team last year after winning a First Four game against Michigan State to just make it into the NCAA Tournament bracket. Two of the starters on that team are keying the Bruins' run this year, guards Jaime Jaquez Jr. and Tyger Campbell.

Jaquez has scored 15 points in each of UCLA's first two tournament games and had nine rebounds with six assists in the first round against Akron. Campbell scored 16 points apiece in those two games and had nine total assists as well. North Carolina is coming off an emotional overtime win against defending national champion Baylor and the Tar Heels have hit 40 percent of their three-pointers over their last two games. That's a switch from the 31.3 percent they had been shooting from beyond the arc in their preceding 10 games.

How to make 2022 NCAA Tournament bracket predictions

SportsLine's model has also identified an underdog that wins in well over 60 percent of simulations in the Sweet 16. It's also calling for a shocking team to make a run to the championship game. With the model's proven track record of calling bracket-busting upsets, you'll want to see which stunners it is calling this year before locking in any bracket picks.

So what's the optimal NCAA Tournament 2022 bracket? And which underdogs shock college basketball? Visit SportsLine now to see which teams you can back with confidence, all from the model that beat over 92 percent of bracket players two of the last three years.