Wilson is set to lead the 49ers backfield again with Elijah Mitchell (knee/concussion) ruled out for Sunday's game against the Falcons, Matt Maiocco of NBC Sports Bay Area reports.

Wilson was disappointing from a fantasy standpoint last week in his second start of the year, finishing without a target and unable to score his first touchdown of the season in a win over the Bengals. He did, however, lead the team with 13 carries, and his 59 percent snap share wasn't too far south of what Mitchell has seen this year (66.1 percent in nine games). The 49ers still have JaMycal Hasty and Kyle Juszczyk for passing downs and wideout Deebo Samuel as a big-play/red-zone threat on the ground, but Wilson is again a strong favorite to lead the team in carries. Furthermore, head coach Kyle Shanahan acknowledged Friday that he isn't especially optimistic about Mitchell's chances of returning for a Thursday game against the Titans in Week 16, Nick Wagoner of ESPN.com reports.

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