NFL Week 17 comes to a close with a high-profile matchup between teams with Super Bowl aspirations when Josh Allen and the Buffalo Bills travel to Cincinnati to take on Joe Burrow and the Cincinnati Bengals on Monday Night Football at Paycor Stadium. The latest Bills vs. Bengals odds from Caesars Sportsbook imply that this MNF game could be a high-scoring affair with an over/under of 49.5 points, making it imperative to hit on the right mix of players from the MNF NFL DFS player pool when building your MNF NFL DFS strategy. In this potential shootout, should Allen and Burrow be considered must-start players in your NFL DFS lineups and NFL DFS stacks on Monday Night Football? Or should you build your MNF DFS rosters around Stefon Diggs, Gabe Davis, James Cook, Dawson Knox, Devin Singletary, Ja'Marr Chase, Joe Mixon, Hayden Hurst or Tee Higgins?

Kickoff is set for 8:20 p.m. ET. Before making any NFL DFS picks for Bengals vs. Bills on sites like DraftKings and FanDuel, be sure to check out the NFL DFS lineup advice, strategy and player stacks from SportsLine NFL daily Fantasy expert Jimmie Kaylor

Kaylor is a NFL and DFS expert for SportsLine, who opened the 2022 NFL season by winning DraftKings' NFL Showdown Thursday Kickoff Millionaire contest. He edged out over 355,000 other entrants in the contest and also has multiple five-figure tournament wins on his DFS resume. Kaylor, who has been cashing big all season, has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America, and his background as a former college and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks.

Kaylor has been spot-on all season, hitting on epic NFL DFS picks like Jerry Jeudy (4-102-1), Stefon Diggs (12-148-3, 6-106-1, 7-92-1), Amari Cooper (7-101-1, 5-131-1), Nick Chubb (23-113-1, 23-101-2), CeeDee Lamb (8-87-1), Deebo Samuel (6-115-1) Cooper Kupp (14-122), Travis Kelce (7-25-4, 10-106), Davante Adams (3-124-2), Justin Fields (179-1-1, 82-1), Derrick Henry (132-2), Jimmy Garoppolo (228-4), Michael Pittman (7-61-1), Christian McCaffrey (26-108-1, 6-30), Kirk Cousins (460-4), Justin Jefferson (12-123-1), J.K. Dobbins (13-125), and T.J. Hockenson (13-109-2). Anyone who has followed his picks is way up.

Now, Kaylor has turned his attention to Bills vs. Bengals on Monday Night Football Week 17 and just locked in his top daily Fantasy football picks. You can only see his picks and analysis at SportsLine.

Top NFL DFS picks for Bengals vs. Bills on MNF

One of Kaylor's favorite DFS picks for the Buffalo vs. Cincinnati MNF game is Bengals wide receiver Ja'Marr Chase. The 22-year-old wideout has quickly established himself as one of the most dynamic playmakers in the NFL, and will likely go over 1,000 yards for the season on Monday night. Chase enters Week 17 with 79 catches for 960 yards and eight touchdowns, despite missing four games with a hip injury. Buffalo has a talented secondary, but with Higgins on the other side, Kaylor is expecting Chase to see plenty of single coverage on MNF.

"There is some rain in the MNF weather forecast, but I am still expecting this matchup to be a high-scoring affair. Both sides are full of offensive playmakers and can light up the scoreboard seemingly at will. For Cincinnati, I am projecting them to lean more heavily on their passing attack on Monday night, and All-Pro wide receiver Ja'Marr Chase should be one of the highest-scoring DFS players on this Showdown slate. Chase missed some time earlier this season, but has still managed to haul in 79 passes for 960 yards and eight touchdowns. For MNF, I have him projected to finish with 7+ receptions for over 100 yards and a touchdown," Kaylor told SportsLine. You can see the rest of Kaylor's NFL DFS picks here.

How to build NFL DFS lineups for Bills vs. Bengals on MNF

Kaylor is also targeting another undervalued player who could explode for huge numbers for Monday Night Football. This pick could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who it is, and the rest of Kaylor's MNF DFS picks, at SportsLine

So who is Jimmie Kaylor including in his optimal NFL DFS lineups for Monday Night Football? And which under-the-radar NFL DFS picks offer huge value? Visit SportsLine now to see optimal NFL DFS picks, rankings, advice, and stacks, all from a DFS expert who already won a single-game millionaire maker tournament in 2022, and find out.