The Astros' Framber Valdez can extend his record of consecutive quality starts by a lefty when he and the Houston Astros visit the Detroit Tigers in the first game of a three-game series on Monday. The 28-year-old Valdez (14-5, 2.64 ERA) has made 23 straight quality starts, a streak that began on April 25. On Monday, he takes on the Tigers' Eduardo Rodriguez (3-4, 4.13). Houston is a -235 favorite in the latest Astros vs. Tigers odds from Caesars Sportsbook, while Detroit is a +192 underdog. The over/under for runs scored is 7.

First pitch is set for 6:40 p.m. ET from Comerica Park. The game is one of nine on the MLB schedule for Monday. Elsewhere in the majors, the Rays and Blue Jays start a key five-game series in Toronto, and the Rangers and Marlins play a doubleheader in Miami. Before making any MLB picks or parlays, be sure to see the predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times, and it is a 316-272 on top-rated MLB money-line picks since the start of the 2021 season. This is the same model that pegged the 2021 Atlanta Braves at 10-1 as one of three best bets to win the World Series. Anybody who has followed the model has seen profitable returns.

Now, the model has locked in four confident MLB best bets for Monday. They all involve games at 6:40 p.m. ET or later, so there's still time to get these MLB picks in. If you successfully parlay the picks, you'd be looking at a payout of more than 11-1. You can only see the model's MLB picks at SportsLine

Top MLB picks today

The model, which ran 10,000 simulations on each of Monday's games, likes Cincinnati (-135) to knock off Pittsburgh. The Reds (56-82) have played much better after a disastrous 3-22 start to the season. Meanwhile, the Pirates (51-88) have done the opposite, going 27-60 since June 6.

Cincinnati enters Monday's game with the edge in starting pitching. Over his last three starts, Reds lefty Mike Minor is 2-0 with a 2.60 ERA. He is coming off a one-run effort across 5.2 innings against the Cubs. Meanwhile, Pittsburgh starter Bryse Wilson has been shelled in his last two starts, giving up six runs in four innings (13.50 ERA). He didn't go longer than three innings in either start. See who else to back right here.

Featured Game | Cincinnati Reds vs. Pittsburgh Pirates

How to make MLB picks and parlays for Monday

The model also locked in three other best bets for Monday, including a play on a big NL underdog. You can see the model's MLB Monday best bets and parlay only at SportsLine.

What MLB picks should you target for a payout of more than 11-1? And what underdog does the model like on Monday? Visit SportsLine now to see the MLB best bets from an advanced model that is on a 316-272 run on top-rated MLB money-line picks since the start of 2021.