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The Atlanta Braves improved to 5-0 against the Arizona Diamondbacks this season with a 6-2 win on Tuesday, extending their winning streak to four games. They are only slight -115 favorites against the Diamondbacks on Wednesday night, according to the latest MLB odds from SportsLine consensus. Arizona rookie pitcher Slade Cecconi is 2-6 with a 6.10 ERA, and he will be on the mound for Wednesday's game. Should you back the Braves at a cheap price with your MLB parlay bets?

Other games on Wednesday's MLB schedule that have been difficult for oddsmakers to nail down include the Rays (-125) vs. Yankees, Cardinals (-125) vs. Royals and Rangers (-130) vs. Angels. Which games should you target with your MLB parlay picks?  Before making any MLB picks or parlays, be sure to check out the MLB predictions and betting advice from SportsLine's proven simulation model.

The SportsLine Projection Model simulates every MLB game 10,000 times. It entered Week 16 of the 2024 MLB season a profitable 49-37 on all-top rated MLB picks this season. Dating back to last season, it is on a 24-9 roll on top-rated run-line picks (+1077). Anybody following has seen strong returns.

For Wednesday, the model has locked in three confident MLB best bets for games that begin at 6:40 p.m. ET or later. If you successfully parlay the picks, you'd be looking at a payout of almost 8-1. You can see the model's MLB picks only at SportsLine. 

Top MLB picks today

After simulating every game on Wednesday 10,000 times, the model is picking the Padres (-139) to beat the Mariners. Seattle picked up an 8-3 win during Tuesday's series opener, but that type of offensive display has been few and far between for the Mariners this season. It was their highest run total since June 22, and they have the worst batting average in the majors (.217).

The model does not expect Seattle to deliver another strong offensive performance on Wednesday, especially since the Padres are starting one of their most reliable pitchers. Michael King is 7-5 with a 3.51 ERA, allowing just one run in a win over Texas his last time out. Mariners starter Bryce Miller has given up at least two earned runs in four straight starts, so San Diego is the side with all the value on Wednesday night. See the model's top MLB picks here.

How to make Wednesday MLB parlays

The model also locked in two other best bets for Wednesday, including backing a large American League underdog. You can see the model's MLB Wednesday best bets and parlay only at SportsLine.

What MLB picks should you target for a payout of almost 8-1? Visit SportsLine now to see the MLB best bets for Wednesday from the model that's on a 24-9 run on top-rated MLB run-line picks, and find out.