| Orioles 1st | |
| Jon Lester pitching: | |
| Brian Roberts: | Strike looking, Ball, Ball, Ball, Strike looking, Roberts doubled to center. |
| Melvin Mora: | Ball, Roberts stole third, Ball, Foul, Ball, Foul, Mora walked. |
| Miguel Tejada: | Ball, Ball, Ball, Strike looking, Strike swinging, Pickoff attempt to first, Foul, Tejada hit sacrifice fly to right, Roberts scored. |
| Jeff Conine: | Foul, Strike looking, Conine singled to center, Mora to second. |
| Jay Gibbons: | Ball, Ball, Gibbons grounded into double play second to first, Conine out at second. |
| End of Inning (1 Run, 2 Hits, 0 Errors) | |
| Red Sox 1st | |
| Daniel Cabrera pitching: | |
| Coco Crisp: | Bunt foul, Ball, Crisp flied out to center. |
| Mark Loretta: | Ball, Ball, Ball, Strike looking, Loretta walked. |
| Kevin Youkilis: | Strike looking, Youkilis doubled to left, Loretta to third. |
| Manny Ramirez: | Foul, Foul, Ball, Ball, Ball, Ramirez walked. |
| Wily Mo Pena: | Ball, Ball, Ball, Strike looking, Foul, Pena struck out swinging. |
| Mike Lowell: | Ball, Ball, Ball, Strike looking, Lowell homered to left center, Loretta, Youkilis and Ramirez scored. |
| Alex Cora: | Ball, Ball, Strike looking, Cora grounded out to first. |
| End of Inning (4 Runs, 2 Hits, 0 Errors) | |
| Orioles 2nd | |
| Jon Lester pitching: | |
| Ramon Hernandez: | Strike looking, Ball, Ball, Strike looking, Ball, Foul, Foul, Hernandez walked. |
| Corey Patterson: | Strike looking, Ball, Foul, Patterson homered to right, Hernandez scored. |
| Kevin Millar: | Ball, Ball, Strike looking, Strike swinging, Millar struck out swinging. |
| Nick Markakis: | Ball, Strike looking, Foul, Foul, Ball, Markakis doubled to center. |
| Brian Roberts: | Ball, Strike looking, Strike looking, Ball, Roberts flied out to center, Markakis to third. |
| Melvin Mora: | Strike looking, Mora singled softly to shallow left center, Markakis scored. |
| Miguel Tejada: | Ball, Tejada singled to right, Mora to second. |
| Jeff Conine: | Ball, Ball, Strike looking, Conine flied out to left. |
| End of Inning (3 Runs, 4 Hits, 0 Errors) | |
| Red Sox 2nd | |
| Daniel Cabrera pitching: | |
| Gabe Kapler: | Ball, Strike looking, Strike looking, Kapler struck out swinging. |
| Doug Mirabelli: | Ball, Mirabelli flied out to right. |
| Coco Crisp: | Ball, Ball, Strike looking, Crisp flied out to left. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
| Orioles 3rd | |
| Jon Lester pitching: | |
| Jay Gibbons: | Foul, Strike swinging, Ball, Gibbons popped out to second. |
| Ramon Hernandez: | Strike looking, Ball, Foul, Hernandez struck out looking. |
| Corey Patterson: | Patterson grounded out to third. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
| Red Sox 3rd | |
| Daniel Cabrera pitching: | |
| Mark Loretta: | Ball, Ball, Ball, Strike looking, Loretta walked. |
| Kevin Youkilis: | Youkilis grounded into fielder's choice to shortstop, Loretta out at second. |
| Manny Ramirez: | Ball, Ramirez flied out to deep right. |
| Wily Mo Pena: | Strike swinging, Ball, Youkilis caught stealing, catcher to second. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
| Orioles 4th | |
| Jon Lester pitching: | |
| Kevin Millar: | Ball, Ball, Foul, Millar flied out to center. |
| Nick Markakis: | Markakis singled to center. |
| Brian Roberts: | Ball, Ball, Roberts flied out to right. |
| Melvin Mora: | Ball, Strike swinging, Pickoff attempt to first, Ball, Ball, Mora singled to left center, Markakis to second. |
| Miguel Tejada: | Foul, Tejada flied out to right. |
| End of Inning (0 Runs, 2 Hits, 0 Errors) | |
| Red Sox 4th | |
| Daniel Cabrera pitching: | |
| Wily Mo Pena: | Strike swinging, Ball, Ball, Foul, Ball, Foul, Pena singled to left center. |
| Mike Lowell: | Ball, Ball, Strike looking, Pickoff attempt to first, Ball, Lowell walked, Pena to second. |
| Alex Cora: | Cora reached on bunt single to pitcher, Pena to third, Lowell to second. |
| Gabe Kapler: | Strike looking, Kapler grounded out to pitcher, Pena scored, Lowell to third, Cora to second. |
| Doug Mirabelli: | Ball, Ball, Lowell scored, Cora to third on wild pitch, Ball, Mirabelli walked. |
| Coco Crisp: | Crisp singled to center, Cora scored, Mirabelli to second. |
| Mark Loretta: | Ball, Ball, Ball, Strike looking, Loretta lined out to left. |
| Kevin Youkilis: | Ball, Strike looking, Strike looking, Ball, Ball, Foul, Youkilis struck out looking. |
| End of Inning (3 Runs, 3 Hits, 0 Errors) | |
| Orioles 5th | |
| Jon Lester pitching: | |
| Jeff Conine: | Strike looking, Foul, Ball, Ball, Ball, Conine struck out swinging. |
| Jay Gibbons: | Strike looking, Strike looking, Ball, Ball, Foul, Ball, Foul, Gibbons flied out to right. |
| Ramon Hernandez: | Ball, Hernandez singled to right. |
| Corey Patterson: | Patterson flied out to center. |
| End of Inning (0 Runs, 1 Hit, 0 Errors) | |
| Red Sox 5th | |
| Russ Ortiz pitching: | |
| Manny Ramirez: | Ball, Ball, Ball, Strike looking, Ramirez lined out to shortstop. |
| Wily Mo Pena: | Ball, Pena grounded out to shortstop. |
| Mike Lowell: | Strike looking, Ball, Ball, Ball, Foul, Lowell flied out to right. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
| Orioles 6th | |
| Kyle Snyder pitching: | |
| Kevin Millar: | Millar homered to left center. |
| Nick Markakis: | Strike looking, Markakis grounded out to first. |
| Brian Roberts: | Strike looking, Ball, Ball, Strike swinging, Roberts homered to right. |
| Melvin Mora: | Strike looking, Foul, Ball, Mora grounded out to third. |
| Miguel Tejada: | Strike looking, Ball, Strike swinging, Tejada struck out swinging. |
| End of Inning (2 Runs, 2 Hits, 0 Errors) | |
| Red Sox 6th | |
| Russ Ortiz pitching: | |
| Alex Cora: | Ball, Cora grounded out to second. |
| Gabe Kapler: | Ball, Ball, Foul, Kapler flied out to deep left. |
| Doug Mirabelli: | Ball, Mirabelli popped out to second. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
| Orioles 7th | |
| Manny Delcarmen pitching: | |
| Jeff Conine: | Conine flied out to left. |
| Jay Gibbons: | Ball, Ball, Gibbons flied out to right. |
| Ramon Hernandez: | Strike looking, Hernandez grounded out to shortstop. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
| Red Sox 7th | |
| Russ Ortiz pitching: | |
| Coco Crisp: | Ball, Strike looking, Ball, Ball, Crisp walked. |
| Todd Williams relieved Russ Ortiz. | |
| Mark Loretta: | Foul, Loretta hit by pitch, Crisp to second. |
| Kevin Youkilis: | Ball, Strike looking, Foul, Ball, Ball, Foul, Youkilis homered to center, Crisp and Loretta scored. |
| Manny Ramirez: | Strike looking, Ball, Ramirez safe at first on Williams' fielding error. |
| Wily Mo Pena: | Strike looking, Foul, Ball, Foul, Ball, Ball, Foul, Pena singled to left center, Ramirez to second. |
| Mike Lowell: | Ball, Strike looking, Lowell flied out to left. |
| Bruce Chen relieved Todd Williams. | |
| Alex Cora: | Strike looking, Foul, Cora struck out swinging. |
| Gabe Kapler: | Strike looking, Ball, Strike swinging, Foul, Foul, Foul, Foul, Kapler popped out to second. |
| End of Inning (3 Runs, 2 Hits, 1 Error) | |
| Orioles 8th | |
| Manny Delcarmen pitching: | |
| Corey Patterson: | Ball, Ball, Patterson fouled out to third. |
| Kevin Millar: | Ball, Ball, Foul, Ball, Foul, Foul, Foul, Millar fouled out to third. |
| Nick Markakis: | Ball, Ball, Strike looking, Strike looking, Ball, Markakis walked. |
| Brian Roberts: | Ball, Ball, Ball, Roberts walked, Markakis to second. |
| Craig Hansen relieved Manny Delcarmen. | |
| Melvin Mora: | Strike looking, Ball, Ball, Ball, Strike looking, Mora singled to right, Markakis scored, Roberts to third. |
| Miguel Tejada: | Strike looking, Tejada fouled out to first. |
| End of Inning (1 Run, 1 Hit, 0 Errors) | |
| Red Sox 8th | |
| Bruce Chen pitching: | |
| Doug Mirabelli: | Ball, Mirabelli homered to center. |
| Coco Crisp: | Crisp flied out to center. |
| Mark Loretta: | Ball, Strike looking, Loretta grounded out to shortstop. |
| Kevin Youkilis: | Ball, Strike looking, Strike swinging, Ball, Youkilis grounded out to third. |
| End of Inning (1 Run, 1 Hit, 0 Errors) | |
| Orioles 9th | |
| Craig Hansen pitching: | |
| Jeff Conine: | Ball, Ball, Strike looking, Ball, Conine singled to center. |
| Jay Gibbons: | Strike looking, Ball, Gibbons popped out to second. |
| Ramon Hernandez: | Strike looking, Ball, Strike looking, Foul, Ball, Hernandez singled to right, Conine to second. |
| Jonathan Papelbon relieved Craig Hansen. | |
| Corey Patterson: | Strike swinging, Strike swinging, Ball, Ball, Foul, Ball, Patterson walked, Conine to third, Hernandez to second. |
| Kevin Millar: | Strike looking, Ball, Millar safe at first on shortstop Cora's fielding error, Conine scored, Hernandez to third, Patterson to second |
| Brandon Fahey ran for Kevin Millar | |
| Brandon Fahey hit for Nick Markakis. | |
| Brandon Fahey: | Ball, Foul, Ball, Ball, Foul, Foul, Fahey struck out swinging. |
| Brian Roberts: | Ball, Ball, Ball, Strike looking, Roberts walked, Hernandez scored, Patterson to third, Fahey to second. |
| Melvin Mora: | Ball, Strike looking, Ball, Strike swinging, Foul, Ball, Foul, Foul, Mora grounded out to third. |
| End of Inning (2 Runs, 2 Hits, 1 Error) | |