| Red Sox 1st | |
| C.C. Sabathia pitching: | |
| Julio Lugo: | Strike looking, Ball, Lugo flied out to deep left. |
| Dustin Pedroia: | Strike looking, Pedroia grounded out to third. |
| Kevin Youkilis: | Ball, Ball, Strike looking, Youkilis singled to left center. |
| Manny Ramirez: | Ball, Strike looking, Ramirez grounded out to third. |
| End of Inning (0 Runs, 1 Hit, 0 Errors) | |
| Indians 1st | |
| Daisuke Matsuzaka pitching: | |
| Grady Sizemore: | Ball, Strike looking, Strike looking, Sizemore singled to center. |
| Casey Blake: | Strike looking, Ball, Strike looking, Sizemore stole second, Blake grounded into fielder's choice to shortstop, Sizemore out at third. |
| Victor Martinez: | Foul, Ball, Foul, Ball, Ball, Foul, Foul, Martinez walked, Blake to second. |
| Travis Hafner: | Foul, Foul, Hafner grounded into fielder's choice to right, Blake to third, Martinez out at second. |
| Ryan Garko: | Ball, Garko hit by pitch, Hafner to second. |
| Jhonny Peralta: | Strike swinging, Ball, Foul, Ball, Peralta struck out swinging. |
| End of Inning (0 Runs, 1 Hit, 0 Errors) | |
| Red Sox 2nd | |
| C.C. Sabathia pitching: | |
| Coco Crisp: | Ball, Strike looking, Strike looking, Ball, Ball, Crisp struck out swinging. |
| Mike Lowell: | Foul, Ball, Lowell flied out to right. |
| Jason Varitek: | Ball, Ball, Strike looking, Strike looking, Varitek grounded out to third. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
| Indians 2nd | |
| Daisuke Matsuzaka pitching: | |
| Trot Nixon: | Nixon flied out to deep right. |
| Ben Francisco: | Ball, Francisco grounded bunt out to pitcher. |
| Josh Barfield: | Strike looking, Barfield flied out to center. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
| Red Sox 3rd | |
| C.C. Sabathia pitching: | |
| J.D. Drew: | Ball, Ball, Foul, Strike looking, Foul, Drew struck out swinging. |
| Wily Mo Pena: | Ball, Foul, Ball, Ball, Pena grounded out to second. |
| Julio Lugo: | Ball, Strike looking, Ball, Lugo flied out to right. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
| Indians 3rd | |
| Daisuke Matsuzaka pitching: | |
| Grady Sizemore: | Ball, Ball, Strike looking, Sizemore singled to left center. |
| Casey Blake: | Ball, Ball, Foul, Foul, Blake flied out to deep left. |
| Victor Martinez: | Pickoff attempt, Strike looking, Foul, Martinez struck out swinging. |
| Travis Hafner: | Strike looking, Strike swinging, Ball (pitchout), Ball, Sizemore stole second, Foul, Hafner grounded out to pitcher. |
| End of Inning (0 Runs, 1 Hit, 0 Errors) | |
| Red Sox 4th | |
| C.C. Sabathia pitching: | |
| Dustin Pedroia: | Strike looking, Foul, Ball, Ball, Ball, Pedroia grounded out to second. |
| Kevin Youkilis: | Strike looking, Ball, Youkilis singled to right. |
| Manny Ramirez: | Strike looking, Ball, Ramirez singled to left center, Youkilis to second. |
| Coco Crisp: | Foul, Strike looking, Ball, Foul, Crisp struck out swinging. |
| Mike Lowell: | Ball, Strike looking, Strike looking, Foul, Lowell singled to left, Youkilis scored, Ramirez to third. |
| Jason Varitek: | Ball, Foul, Ball, Varitek fouled out to first. |
| End of Inning (1 Run, 3 Hits, 0 Errors) | |
| Indians 4th | |
| Daisuke Matsuzaka pitching: | |
| Ryan Garko: | Strike looking, Ball, Garko doubled to left. |
| Jhonny Peralta: | Peralta grounded out to shortstop. |
| Trot Nixon: | Ball, Strike looking, Ball, Ball, Nixon walked. |
| Ben Francisco: | Strike looking, Ball, Strike swinging, Ball, Francisco struck out on foul tip. |
| Josh Barfield: | Strike looking, Foul, Barfield struck out swinging. |
| End of Inning (0 Runs, 1 Hit, 0 Errors) | |
| Red Sox 5th | |
| C.C. Sabathia pitching: | |
| J.D. Drew: | Strike looking, Foul, Drew struck out swinging. |
| Wily Mo Pena: | Foul, Strike (foul tip), Ball, Ball, Pena struck out looking. |
| Julio Lugo: | Ball, Lugo grounded out to pitcher. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
| Indians 5th | |
| Daisuke Matsuzaka pitching: | |
| Grady Sizemore: | Strike looking, Ball, Ball, Strike swinging, Sizemore struck out swinging. |
| Casey Blake: | Ball, Blake flied out to deep left. |
| Victor Martinez: | Ball, Ball, Ball, Foul, Martinez walked. |
| Travis Hafner: | Hafner grounded out to second. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
| Red Sox 6th | |
| C.C. Sabathia pitching: | |
| Dustin Pedroia: | Pedroia flied out to center. |
| Kevin Youkilis: | Ball, Strike swinging, Youkilis grounded out to third. |
| Manny Ramirez: | Ball, Ball, Strike looking, Ball, Foul, Ramirez reached on an infield single. |
| Coco Crisp: | Strike looking, Crisp grounded into fielder's choice to third, Ramirez out at second. |
| End of Inning (0 Runs, 1 Hit, 0 Errors) | |
| Indians 6th | |
| Daisuke Matsuzaka pitching: | |
| Ryan Garko: | Strike looking, Ball, Ball, Garko flied out to left. |
| Jhonny Peralta: | Foul, Strike looking, Ball, Ball, Peralta fouled out to third. |
| Trot Nixon: | Ball, Nixon popped out to second. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
| Red Sox 7th | |
| C.C. Sabathia pitching: | |
| Mike Lowell: | Strike looking, Strike looking, Foul, Ball, Ball, Ball, Foul, Lowell grounded out to shortstop. |
| Jason Varitek: | Ball, Ball, Strike swinging, Strike looking, Foul, Varitek struck out swinging. |
| J.D. Drew: | Strike swinging, Strike swinging, Drew struck out swinging. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
| Indians 7th | |
| Daisuke Matsuzaka pitching: | |
| Ben Francisco: | Ball, Ball, Francisco singled to left center. |
| Josh Barfield: | Bunt foul, Barfield grounded into fielder's choice to first, Francisco out at second. |
| Grady Sizemore: | Sizemore flied out to center. |
| Casey Blake: | Pickoff attempt, Ball, Strike looking, Barfield stole second, Blake flied out to right. |
| End of Inning (0 Runs, 1 Hit, 0 Errors) | |
| Red Sox 8th | |
| Rafael Betancourt pitching: | |
| Wily Mo Pena: | Ball, Pena grounded out to second. |
| Julio Lugo: | Ball, Lugo doubled to deep left center. |
| Dustin Pedroia: | Ball, Ball, Pedroia fouled out to catcher. |
| Kevin Youkilis: | Strike looking, Foul, Ball, Foul, Youkilis lined out to left. |
| End of Inning (0 Runs, 1 Hit, 0 Errors) | |
| Indians 8th | |
| Hideki Okajima pitching: | |
| Victor Martinez: | Hideki Okajima relieved Daisuke Matsuzaka, Ball, Ball, Ball, Strike looking, Strike swinging, Foul, Foul, Martinez flied out to deep right. |
| Travis Hafner: | Strike looking, Hafner flied out to left. |
| Ryan Garko: | Ball, Strike looking, Strike looking, Garko grounded out to third. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
| Red Sox 9th | |
| Rafael Betancourt pitching: | |
| Manny Ramirez: | Strike looking, Ball, Ball, Foul, Foul, Ramirez struck out looking. |
| Coco Crisp: | Strike looking, Ball, Crisp grounded bunt out to pitcher. |
| Mike Lowell: | Foul, Lowell grounded out to shortstop. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
| Indians 9th | |
| Jonathan Papelbon pitching: | |
| Jhonny Peralta: | Ball, Foul, Foul, Foul, Peralta popped out to second. |
| Trot Nixon: | Strike looking, Ball, Strike looking, Nixon struck out swinging. |
| Ben Francisco: | Foul, Strike looking, Francisco struck out looking. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
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