| Orioles 1st | |
| Bartolo Colon pitching: | |
| Brian Roberts: | Strike looking, Roberts flied out to left. |
| Nick Markakis: | Strike looking, Ball, Ball, Foul, Foul, Markakis struck out swinging. |
| Melvin Mora: | Strike looking, Ball, Ball, Foul, Foul, Ball, Mora flied out to center. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
| Red Sox 1st | |
| Garrett Olson pitching: | |
| Jacoby Ellsbury: | Strike looking, Foul, Ellsbury singled to center. |
| Dustin Pedroia: | Strike looking, Pedroia popped out to second. |
| J.D. Drew: | Pickoff attempt, Ball, Ball, Foul, Pickoff attempt, Ellsbury to third on Olson's throwing error, Strike swinging, Drew doubled to right, Ellsbury scored. |
| Manny Ramirez: | Ball, Ball, Ramirez grounded out to second, Drew to third. |
| Mike Lowell: | Ball, Ball, Ball, Lowell walked, Drew scored on wild pitch. |
| Kevin Youkilis: | Strike looking, Foul, Pickoff attempt, Ball, Ball, Foul, Foul, Ball, Youkilis walked, Lowell to second. |
| Jason Varitek: | Strike looking, Ball, Ball, Ball, Varitek homered to left, Lowell and Youkilis scored. |
| Coco Crisp: | Crisp lined out to right. |
| End of Inning (5 Runs, 3 Hits, 1 Error) | |
| Orioles 2nd | |
| Bartolo Colon pitching: | |
| Aubrey Huff: | Strike looking, Strike looking, Huff singled to left. |
| Kevin Millar: | Ball, Strike looking, Foul, Ball, Ball, Millar grounded into double play third to second to first, Huff out at second. |
| Luke Scott: | Ball, Strike swinging, Foul, Ball, Scott ground-rule doubled to right. |
| Ramon Hernandez: | Strike looking, Ball, Strike looking, Foul, Hernandez struck out swinging. |
| End of Inning (0 Runs, 2 Hits, 0 Errors) | |
| Red Sox 2nd | |
| Garrett Olson pitching: | |
| Julio Lugo: | Ball, Ball, Ball, Lugo singled to left center. |
| Jacoby Ellsbury: | Foul, Ellsbury fouled out to third. |
| Dustin Pedroia: | Strike looking, Pedroia fouled out to catcher. |
| J.D. Drew: | Strike looking, Ball, Ball, Pickoff attempt, Strike looking, Lugo stole second, Ball, Drew grounded out to pitcher. |
| End of Inning (0 Runs, 1 Hit, 0 Errors) | |
| Orioles 3rd | |
| Bartolo Colon pitching: | |
| Adam Jones: | Ball, Strike swinging, Foul, Jones struck out swinging. |
| Freddie Bynum: | Strike looking, Foul, Bynum struck out looking. |
| Brian Roberts: | Foul, Ball, Ball, Roberts flied out to left. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
| Red Sox 3rd | |
| Garrett Olson pitching: | |
| Manny Ramirez: | Foul, Ramirez singled to left. |
| Mike Lowell: | Strike looking, Lowell flied out to center. |
| Kevin Youkilis: | Ball, Ball, Ball, Strike looking, Youkilis walked, Ramirez to second. |
| Jason Varitek: | Foul, Foul, Varitek grounded into double play second to shortstop to first, Youkilis out at second. |
| End of Inning (0 Runs, 1 Hit, 0 Errors) | |
| Orioles 4th | |
| Bartolo Colon pitching: | |
| Nick Markakis: | Ball, Foul, Ball, Strike swinging, Markakis singled to right. |
| Melvin Mora: | Ball, Strike looking, Ball, Strike looking, Mora lined out to right. |
| Aubrey Huff: | Ball, Ball, Huff popped out to third. |
| Kevin Millar: | Ball, Foul, Foul, Millar struck out looking. |
| End of Inning (0 Runs, 1 Hit, 0 Errors) | |
| Red Sox 4th | |
| Garrett Olson pitching: | |
| Coco Crisp: | Ball, Strike looking, Foul, Crisp safe at first on shortstop Bynum's fielding error. |
| Julio Lugo: | Lugo grounded into double play shortstop to first, Crisp out at second. |
| Jacoby Ellsbury: | Ball, Ball, Foul, Ellsbury grounded out to second. |
| End of Inning (0 Runs, 0 Hits, 1 Error) | |
| Orioles 5th | |
| Bartolo Colon pitching: | |
| Luke Scott: | Ball, Strike looking, Scott homered to right. |
| Ramon Hernandez: | Hernandez lined out to third. |
| Adam Jones: | Ball, Ball, Foul, Jones flied out to deep left. |
| Freddie Bynum: | Ball, Ball, Ball, Bynum walked. |
| Brian Roberts: | Pickoff attempt, Pickoff attempt, Ball, Roberts flied out to left. |
| End of Inning (1 Run, 1 Hit, 0 Errors) | |
| Red Sox 5th | |
| Garrett Olson pitching: | |
| Dustin Pedroia: | Ball, Foul, Foul, Ball, Pedroia grounded out to third. |
| J.D. Drew: | Strike looking, Ball, Foul, Ball, Drew lined out to shortstop. |
| Manny Ramirez: | Strike swinging, Strike swinging, Ball, Foul, Ramirez flied out to right. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
| Orioles 6th | |
| Bartolo Colon pitching: | |
| Nick Markakis: | Ball, Strike looking, Markakis grounded out to first. |
| Melvin Mora: | Ball, Strike looking, Mora ground-rule doubled to right. |
| Aubrey Huff: | Strike looking, Ball, Strike looking, Foul, Ball, Foul, Ball, Huff struck out looking. |
| Kevin Millar: | Foul, Foul, Millar struck out swinging. |
| End of Inning (0 Runs, 1 Hit, 0 Errors) | |
| Red Sox 6th | |
| Garrett Olson pitching: | |
| Mike Lowell: | Ball, Strike looking, Foul, Ball, Foul, Foul, Lowell homered to left. |
| Kevin Youkilis: | Strike looking, Strike looking, Foul, Ball, Ball, Foul, Youkilis doubled to deep left center. |
| Jason Varitek: | Strike looking, Ball, Varitek grounded out to shortstop. |
| Coco Crisp: | Lance Cormier relieved Garrett Olson, Ball, Strike looking, Strike looking, Ball, Crisp lined out to right. |
| Julio Lugo: | Strike looking, Strike looking, Ball, Ball, Lugo struck out swinging. |
| End of Inning (1 Run, 2 Hits, 0 Errors) | |
| Orioles 7th | |
| David Aardsma pitching: | |
| Luke Scott: | Ball, Ball, Ball, Strike looking, Foul, Foul, Scott struck out swinging. |
| Ramon Hernandez: | Strike swinging, Strike looking, Hernandez flied out to deep right. |
| Adam Jones: | Ball, Ball, Ball, Strike looking, Strike looking, Jones doubled to right. |
| Freddie Bynum: | Strike looking, Strike swinging, Foul, Bynum struck out swinging. |
| End of Inning (0 Runs, 1 Hit, 0 Errors) | |
| Red Sox 7th | |
| Lance Cormier pitching: | |
| Jacoby Ellsbury: | Strike looking, Strike looking, Ball, Ellsbury grounded out to right. |
| Dustin Pedroia: | Ball, Strike swinging, Pedroia grounded out to center. |
| J.D. Drew: | Ball, Ball, Ball, Drew walked. |
| Manny Ramirez: | Ball, Strike looking, Ball, Ball, Ramirez walked, Drew to second. |
| Mike Lowell: | Ball, Ball, Strike looking, Strike looking, Ball, Lowell walked, Drew to third, Ramirez to second. |
| Kevin Youkilis: | Ball, Ball, Strike looking, Foul, Youkilis reached on fielder's choice to third, Ramirez out at third, Lowell to second. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
| Orioles 8th | |
| Javier Lopez pitching: | |
| Brian Roberts: | Strike looking, Strike looking, Roberts struck out swinging. |
| Nick Markakis: | Ball, Ball, Strike looking, Ball, Markakis walked. |
| Melvin Mora: | Mora grounded into double play third to second to first, Markakis out at second. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
| Red Sox 8th | |
| Dennis Sarfate pitching: | |
| Jason Varitek: | Strike looking, Strike looking, Ball, Foul, Varitek struck out swinging. |
| Coco Crisp: | Ball, Ball, Foul, Foul, Crisp grounded out to pitcher. |
| Julio Lugo: | Strike swinging, Foul, Foul, Lugo struck out swinging. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
| Orioles 9th | |
| Kevin Cash catching | |
| Mike Timlin pitching: | |
| Aubrey Huff: | Strike looking, Foul, Foul, Foul, Huff doubled to right. |
| Kevin Millar: | Ball, Millar doubled to deep left center, Huff scored. |
| Luke Scott: | Ball, Ball, Foul, Scott grounded out to second, Millar to third. |
| Ramon Hernandez: | Foul, Ball, Ball, Hernandez lined out to first. |
| Adam Jones: | Strike looking, Ball, Jones safe at first on 2nd baseman Pedroia's fielding error, Millar scored |
| Oscar Salazar hit for Freddie Bynum. | |
| Oscar Salazar: | Strike looking, Ball, Ball, Salazar singled to shallow left center, Jones to second. |
| Jonathan Papelbon relieved Mike Timlin. | |
| Brian Roberts: | Foul, Ball, Foul, Foul, Roberts grounded out to first. |
| End of Inning (2 Runs, 3 Hits, 1 Error) | |
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