| Red Sox 1st | |
| Jeremy Guthrie pitching: | |
| Jacoby Ellsbury: | Strike looking, Ball, Ellsbury flied out to deep left. |
| Dustin Pedroia: | Strike looking, Pedroia flied out to center. |
| David Ortiz: | Ball, Strike looking, Foul, Ortiz doubled to center. |
| Kevin Youkilis: | Ball, Ball, Strike swinging, Ball, Youkilis grounded out to catcher. |
| End of Inning (0 Runs, 1 Hit, 0 Errors) | |
| Orioles 1st | |
| Jon Lester pitching: | |
| Brian Roberts: | Ball, Ball, Strike looking, Roberts flied out to right. |
| Nick Markakis: | Markakis flied out to left. |
| Melvin Mora: | Ball, Foul, Mora fouled out to catcher. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
| Red Sox 2nd | |
| Jeremy Guthrie pitching: | |
| Jason Bay: | Strike looking, Ball, Ball, Bay homered to center. |
| Jed Lowrie: | Ball, Lowrie flied out to deep left. |
| Sean Casey: | Strike looking, Strike swinging, Foul, Casey popped out to left. |
| Jason Varitek: | Ball, Ball, Varitek homered to right. |
| Coco Crisp: | Crisp reached on bunt single to catcher. |
| Jacoby Ellsbury: | Ellsbury flied out to left. |
| End of Inning (2 Runs, 3 Hits, 0 Errors) | |
| Orioles 2nd | |
| Jon Lester pitching: | |
| Aubrey Huff: | Strike looking, Strike looking, Ball, Foul, Foul, Huff grounded out to pitcher. |
| Ramon Hernandez: | Ball, Hernandez singled to shallow left center. |
| Kevin Millar: | Ball, Strike looking, Ball, Millar fouled out to third. |
| Luke Scott: | Strike looking, Ball, Foul, Scott struck out swinging. |
| End of Inning (0 Runs, 1 Hit, 0 Errors) | |
| Red Sox 3rd | |
| Jeremy Guthrie pitching: | |
| Dustin Pedroia: | Pedroia fouled out to first. |
| David Ortiz: | Ball, Strike looking, Foul, Ball, Ortiz lined out to first. |
| Kevin Youkilis: | Strike looking, Ball, Ball, Ball, Youkilis walked. |
| Jason Bay: | Strike looking, Foul, Ball, Ball, Ball, Bay grounded out to third. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
| Orioles 3rd | |
| Jon Lester pitching: | |
| Jay Payton: | Ball, Foul, Ball, Strike looking, Payton struck out swinging. |
| Juan Castro: | Strike looking, Ball, Ball, Ball, Strike looking, Castro popped out to second. |
| Brian Roberts: | Strike looking, Foul, Foul, Ball, Roberts singled to right. |
| Nick Markakis: | Ball, Ball, Strike looking, Markakis grounded out to shortstop. |
| End of Inning (0 Runs, 1 Hit, 0 Errors) | |
| Red Sox 4th | |
| Jeremy Guthrie pitching: | |
| Jed Lowrie: | Ball, Strike swinging, Foul, Lowrie struck out swinging. |
| Sean Casey: | Strike swinging, Foul, Casey struck out looking. |
| Jason Varitek: | Ball, Ball, Ball, Strike looking, Varitek walked. |
| Coco Crisp: | Strike swinging, Strike swinging, Ball, Ball, Crisp struck out looking. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
| Orioles 4th | |
| Jon Lester pitching: | |
| Melvin Mora: | Foul, Foul, Ball, Mora grounded out to third. |
| Aubrey Huff: | Ball, Ball, Huff homered to center. |
| Ramon Hernandez: | Ball, Ball, Strike swinging, Hernandez grounded out to third. |
| Kevin Millar: | Strike looking, Ball, Ball, Ball, Millar walked. |
| Luke Scott: | Strike swinging, Scott popped out to shortstop. |
| End of Inning (1 Run, 1 Hit, 0 Errors) | |
| Red Sox 5th | |
| Jeremy Guthrie pitching: | |
| Jacoby Ellsbury: | Strike looking, Ellsbury grounded out to pitcher. |
| Dustin Pedroia: | Ball, Ball, Ball, Pedroia walked. |
| David Ortiz: | Strike looking, Ortiz grounded into double play first to shortstop to first, Pedroia out at second. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
| Orioles 5th | |
| Jon Lester pitching: | |
| Jay Payton: | Payton fouled out to catcher. |
| Juan Castro: | Strike looking, Ball, Ball, Castro grounded out to shortstop. |
| Brian Roberts: | Ball, Strike looking, Ball, Strike looking, Ball, Foul, Roberts flied out to center. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
| Red Sox 6th | |
| Jeremy Guthrie pitching: | |
| Kevin Youkilis: | Strike looking, Ball, Ball, Ball, Strike looking, Youkilis flied out to left. |
| Jason Bay: | Strike looking, Bay singled to left. |
| Jed Lowrie: | Pickoff attempt, Ball, Ball, Lowrie flied out to deep left. |
| Sean Casey: | Ball, Ball, Bay stole second, Strike looking, Ball, Foul, Foul, Casey struck out looking. |
| End of Inning (0 Runs, 1 Hit, 0 Errors) | |
| Orioles 6th | |
| Jon Lester pitching: | |
| Nick Markakis: | Strike looking, Foul, Ball, Foul, Markakis struck out swinging. |
| Melvin Mora: | Strike looking, Foul, Mora struck out swinging. |
| Aubrey Huff: | Ball, Strike looking, Ball, Huff lined out to first. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
| Red Sox 7th | |
| Jeremy Guthrie pitching: | |
| Jason Varitek: | Ball, Ball, Varitek grounded out to first. |
| Coco Crisp: | Ball, Strike looking, Ball, Bunt foul, Ball, Crisp walked. |
| Jacoby Ellsbury: | Ball, Ball, Crisp caught stealing, catcher to shortstop, Ball, Ellsbury walked. |
| Dustin Pedroia: | Strike looking, Pedroia popped out to shortstop. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
| Orioles 7th | |
| Jon Lester pitching: | |
| Ramon Hernandez: | Strike swinging, Ball, Ball, Strike swinging, Ball, Foul, Foul, Hernandez flied out to right. |
| Kevin Millar: | Strike looking, Strike looking, Millar doubled to deep left center. |
| Luke Scott: | Ball, Ball, Strike looking, Foul, Ball, Scott struck out swinging. |
| Jay Payton: | Ball, Payton grounded out to third. |
| End of Inning (0 Runs, 1 Hit, 0 Errors) | |
| Red Sox 8th | |
| Rocky Cherry pitching: | |
| David Ortiz: | Ball, Ball, Strike looking, Ortiz safe at first on 1st baseman Millar's fielding error. |
| Kevin Youkilis: | Strike looking, Strike looking, Youkilis struck out swinging. |
| Jason Bay: | Ball, Strike looking, Ball, Bay homered to center, Ortiz scored. |
| Jed Lowrie: | Strike looking, Strike swinging, Ball, Ball, Ball, Lowrie walked. |
| Sean Casey: | Pickoff attempt, Strike looking, Casey singled to left, Lowrie to second, Lowrie to third. |
| Jason Varitek: | Alex Cora ran for Sean Casey, Strike looking, Ball, Ball, Strike swinging, Varitek struck out swinging. |
| Coco Crisp: | Strike looking, Ball, Foul, Ball, Cora to second, Ball, Crisp walked. |
| Alberto Castillo relieved Rocky Cherry. | |
| Jacoby Ellsbury: | Strike looking, Ellsbury grounded out to second. |
| End of Inning (2 Runs, 2 Hits, 1 Error) | |
| Orioles 8th | |
| Alex Cintron hit for Juan Castro | |
| Manny Delcarmen pitching: | |
| Alex Cintron: | Ball, Strike looking, Strike swinging, Ball, Foul, Foul, Foul, Ball, Cintron grounded out to shortstop. |
| Brian Roberts: | Strike looking, Strike looking, Ball, Roberts struck out looking. |
| Nick Markakis: | Ball, Ball, Strike swinging, Strike looking, Ball, Foul, Markakis walked. |
| Melvin Mora: | Ball, Ball, Strike looking, Ball, Mora walked, Markakis to second. |
| Jonathan Papelbon relieved Manny Delcarmen. | |
| Aubrey Huff: | Ball, Ball, Huff doubled to center, Markakis and Mora scored. |
| Ramon Hernandez: | Strike swinging, Hernandez flied out to right. |
| End of Inning (2 Runs, 1 Hit, 0 Errors) | |
| Red Sox 9th | |
| Jim R. Johnson pitching: | |
| Dustin Pedroia: | Strike looking, Foul, Pedroia singled to shallow left center. |
| David Ortiz: | Ball, Foul, Ortiz doubled to center, Pedroia scored. |
| Kevin Youkilis: | Ball, Strike looking, Foul, Youkilis grounded out to second, Ortiz to third. |
| Jason Bay: | Ball, Bay reached on fielder's choice to shortstop, Ortiz scored. |
| Jed Lowrie: | Ball, Strike looking, Strike looking, Ball, Ball, Foul, Lowrie reached on fielder's choice to second, Bay out at second. |
| Alex Cora: | Strike looking, Ball, Ball, Ball, Cora walked, Lowrie to second. |
| Randor Bierd relieved Jim R. Johnson. | |
| Jason Varitek: | Strike looking, Ball, Pickoff attempt, Ball, Foul, Varitek struck out looking. |
| End of Inning (2 Runs, 2 Hits, 0 Errors) | |
| Orioles 9th | |
| Jonathan Papelbon pitching: | |
| Kevin Millar: | Foul, Foul, Ball, Millar popped out to second. |
| Luke Scott: | Strike looking, Ball, Strike looking, Foul, Foul, Scott fouled out to catcher. |
| Jay Payton: | Payton grounded out to second. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
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