| Red Sox 1st | |
| Daniel Cabrera pitching: | |
| Jacoby Ellsbury: | Strike looking, Ellsbury singled to right. |
| Dustin Pedroia: | Ball, Ball, Strike looking, Ellsbury stole second, Ellsbury to third on Hernandez's throwing error, Foul, Ball, Foul, Pedroia walked. |
| David Ortiz: | Ball, Foul, Ball, Strike swinging, Ball, Ortiz singled to center, Ellsbury scored, Pedroia to second. |
| Kevin Youkilis: | Ball, Strike looking, Ball, Youkilis flied out to center, Pedroia to third. |
| Jason Bay: | Foul, Ball, Ball, Strike looking, Foul, Bay hit sacrifice fly to left, Pedroia scored. |
| Sean Casey: | Ball, Strike looking, Casey grounded out to second. |
| End of Inning (2 Runs, 2 Hits, 1 Error) | |
| Orioles 1st | |
| Daisuke Matsuzaka pitching: | |
| Brian Roberts: | Foul, Ball, Foul, Roberts singled to center. |
| Nick Markakis: | Ball, Strike looking, Roberts stole second, Ball, Ball, Markakis walked. |
| Melvin Mora: | Strike swinging, Ball, Ball, Foul, Mora struck out swinging. |
| Aubrey Huff: | Ball, Strike looking, Foul, Huff struck out looking. |
| Ramon Hernandez: | Strike looking, Ball, Ball, Hernandez flied out to right. |
| End of Inning (0 Runs, 1 Hit, 0 Errors) | |
| Red Sox 2nd | |
| Daniel Cabrera pitching: | |
| Jason Varitek: | Ball, Ball, Ball, Strike looking, Varitek homered to right. |
| Alex Cora: | Strike looking, Ball, Cora grounded out to second. |
| Coco Crisp: | Crisp flied out to left. |
| Jacoby Ellsbury: | Ball, Foul, Ellsbury grounded out to catcher. |
| End of Inning (1 Run, 1 Hit, 0 Errors) | |
| Orioles 2nd | |
| Daisuke Matsuzaka pitching: | |
| Luke Scott: | Ball, Foul, Foul, Ball, Ball, Foul, Scott walked. |
| Kevin Millar: | Ball, Strike looking, Foul, Ball, Millar lined out to right. |
| Jay Payton: | Strike looking, Payton safe at first on shortstop Cora's fielding error, Scott to second. |
| Juan Castro: | Foul, Ball, Ball, Castro grounded into double play second to shortstop, Payton out at second. |
| End of Inning (0 Runs, 0 Hits, 1 Error) | |
| Red Sox 3rd | |
| Daniel Cabrera pitching: | |
| Dustin Pedroia: | Strike looking, Ball, Pedroia grounded out to first. |
| David Ortiz: | Strike looking, Ball, Foul, Ball, Ball, Ortiz walked. |
| Kevin Youkilis: | Strike looking, Youkilis flied out to center. |
| Jason Bay: | Ball, Strike looking, Bay grounded into fielder's choice to shortstop, Ortiz out at second. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
| Orioles 3rd | |
| Daisuke Matsuzaka pitching: | |
| Brian Roberts: | Strike looking, Ball, Strike swinging, Roberts struck out swinging. |
| Nick Markakis: | Ball, Ball, Strike looking, Markakis flied out to deep left. |
| Melvin Mora: | Strike looking, Ball, Mora singled to right. |
| Aubrey Huff: | Ball, Foul, Ball, Strike looking, Foul, Ball, Mora to second on wild pitch, Huff walked. |
| Ramon Hernandez: | Strike swinging, Strike looking, Foul, Foul, Hernandez singled to right, Mora scored, Huff to second. |
| Luke Scott: | Scott singled to center, Huff scored, Hernandez to second. |
| Kevin Millar: | Strike looking, Ball, Strike swinging, Millar struck out swinging. |
| End of Inning (2 Runs, 3 Hits, 0 Errors) | |
| Red Sox 4th | |
| Daniel Cabrera pitching: | |
| Sean Casey: | Ball, Ball, Foul, Casey singled to right. |
| Jason Varitek: | Strike looking, Strike looking, Ball, Varitek struck out swinging. |
| Alex Cora: | Strike looking, Ball, Cora singled to center, Casey out at second, Cora to second. |
| Coco Crisp: | Strike looking, Ball, Strike looking, Foul, Crisp reached on an infield single, Cora to third. |
| Jacoby Ellsbury: | Ball, Ball, Foul, Ball, Foul, Ellsbury struck out looking. |
| End of Inning (0 Runs, 3 Hits, 0 Errors) | |
| Orioles 4th | |
| Daisuke Matsuzaka pitching: | |
| Jay Payton: | Ball, Ball, Payton grounded out to shortstop. |
| Juan Castro: | Strike looking, Castro singled to center. |
| Brian Roberts: | Roberts singled to deep left center, Castro to third. |
| Nick Markakis: | Ball, Ball, Ball, Markakis walked, Roberts to second. |
| Melvin Mora: | Ball, Ball, Foul, Ball, Strike swinging, Foul, Mora struck out swinging. |
| Aubrey Huff: | Foul, Ball, Ball, Strike looking, Huff popped out to third. |
| End of Inning (0 Runs, 2 Hits, 0 Errors) | |
| Red Sox 5th | |
| Daniel Cabrera pitching: | |
| Dustin Pedroia: | Pedroia doubled to left. |
| David Ortiz: | Ortiz lined out to left, Pedroia to third. |
| Kevin Youkilis: | Strike looking, Ball, Youkilis homered to left center, Pedroia scored. |
| Jason Bay: | Strike looking, Ball, Bay singled to left center. |
| Sean Casey: | Ball, Strike swinging, Ball, Foul, Pickoff attempt, Ball, Foul, Casey walked, Bay to second. |
| Jason Varitek: | Alberto Castillo relieved Daniel Cabrera, Ball, Strike looking, Ball, Strike looking, Foul, Varitek doubled to center, Bay scored, Casey to third. |
| Alex Cora: | Strike looking, Ball, Foul, Cora flied out to center. |
| Coco Crisp: | Ball, Strike looking, Ball, Foul, Crisp struck out looking. |
| End of Inning (3 Runs, 4 Hits, 0 Errors) | |
| Orioles 5th | |
| Daisuke Matsuzaka pitching: | |
| Ramon Hernandez: | Strike looking, Foul, Hernandez flied out to right. |
| Luke Scott: | Ball, Ball, Strike looking, Ball, Scott walked. |
| Kevin Millar: | Ball, Strike looking, Strike looking, Ball, Millar struck out swinging. |
| Jay Payton: | Ball, Payton grounded out to shortstop. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
| Red Sox 6th | |
| Alberto Castillo pitching: | |
| Jacoby Ellsbury: | Ball, Ellsbury flied out to center. |
| Dustin Pedroia: | Pedroia grounded bunt out to pitcher. |
| David Ortiz: | Ortiz singled to left center. |
| Kevin Youkilis: | Ball, Strike looking, Foul, Ball, Youkilis singled to center, Ortiz to second. |
| Lance Cormier relieved Alberto Castillo. | |
| Jason Bay: | Foul, Strike looking, Foul, Bay struck out looking. |
| End of Inning (0 Runs, 2 Hits, 0 Errors) | |
| Orioles 6th | |
| Javier Lopez pitching: | |
| Juan Castro: | Castro grounded out to shortstop. |
| Brian Roberts: | Foul, Ball, Strike swinging, Ball, Foul, Roberts grounded out to third. |
| Nick Markakis: | Strike looking, Ball, Ball, Markakis grounded out to third. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
| Red Sox 7th | |
| Lance Cormier pitching: | |
| Sean Casey: | Ball, Strike swinging, Strike looking, Ball, Foul, Foul, Casey struck out swinging. |
| Jason Varitek: | Strike swinging, Ball, Ball, Varitek grounded out to shortstop. |
| Alex Cora: | Ball, Ball, Cora flied out to right. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
| Orioles 7th | |
| Jed Lowrie at third | |
| Justin Masterson pitching: | |
| Melvin Mora: | Ball, Strike looking, Ball, Strike looking, Mora struck out swinging. |
| Aubrey Huff: | Ball, Strike looking, Strike looking, Ball, Huff struck out swinging. |
| Ramon Hernandez: | Ball, Foul, Ball, Hernandez grounded out to third. |
| End of Inning (0 Runs, 0 Hits, 0 Errors) | |
| Red Sox 8th | |
| Lance Cormier pitching: | |
| Coco Crisp: | Strike looking, Foul, Ball, Crisp grounded out to second. |
| Jacoby Ellsbury: | Strike looking, Strike looking, Ellsbury singled to center. |
| Dustin Pedroia: | Ball, Ellsbury stole second, Ball, Ball, Strike looking, Strike swinging, Pedroia grounded out to shortstop. |
| David Ortiz: | Intentional ball, Intentional ball, Intentional ball, Ortiz intentionally walked. |
| Kevin Youkilis: | Youkilis singled to left center, Ellsbury scored, Ortiz to second. |
| Jason Bay: | Ball, Strike swinging, Strike looking, Bay grounded into fielder's choice to shortstop, Youkilis out at second. |
| End of Inning (1 Run, 2 Hits, 0 Errors) | |
| Orioles 8th | |
| Jeff Bailey at first | |
| Justin Masterson pitching: | |
| Luke Scott: | Ball, Strike swinging, Scott flied out to right. |
| Kevin Millar: | Strike looking, Strike swinging, Foul, Millar singled to left center. |
| Jay Payton: | Foul, Ball, Payton grounded into double play shortstop to second to first, Millar out at second. |
| End of Inning (0 Runs, 1 Hit, 0 Errors) | |
| Red Sox 9th | |
| Randor Bierd pitching: | |
| Jed Lowrie: | Strike looking, Ball, Lowrie singled to right. |
| Jason Varitek: | Ball, Varitek flied out to center. |
| Alex Cora: | Strike looking, Cora grounded out to first, Lowrie to second. |
| Coco Crisp: | Ball, Ball, Ball, Strike looking, Crisp walked. |
| Jacoby Ellsbury: | Strike looking, Strike swinging, Ellsbury struck out swinging. |
| End of Inning (0 Runs, 1 Hit, 0 Errors) | |
| Orioles 9th | |
| Manny Delcarmen pitching: | |
| Juan Castro: | Ball, Castro flied out to right. |
| Brian Roberts: | Strike looking, Strike looking, Ball, Ball, Foul, Ball, Roberts singled softly to center. |
| Nick Markakis: | Strike looking, Markakis reached on an infield single, Roberts to second. |
| Melvin Mora: | Ball, Bunt foul, Mora grounded out to pitcher, Roberts to third, Markakis to second. |
| Aubrey Huff: | Ball, Strike looking, Ball, Foul, Huff grounded out to third. |
| End of Inning (0 Runs, 2 Hits, 0 Errors) | |